Solidot
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衰老细胞与癌细胞共享特征
http://solidot.org.feedsportal.com/c/33236/f/556826/s/3475d982/sc/17/l/0L0Ssolidot0Borg0Cstory0Dsid0F37511/story01.htm
Dec 5th 2013, 12:20
年龄越大,人类罹患癌症的风险越高,因为积累的环境和化学毒素随着年龄的增长而增长,增加了致癌突变的风险。但风险不是以线性方式上升。为什么风险会随衰老而急剧增加,科学家对此知之甚少。根据发表在《Nature Cell Biology》上的研究报告,科学家发现,衰老细胞和癌细胞的DNA化学修饰存在相似性。他们跟踪了纤维母细胞的衰老过程,发现衰老细胞对表观基因组的控制下降,导致DNA修饰出现广泛的变化。比较衰老细胞和癌细胞的表观遗传变化,可以发现两者存在相似性,共享了某些特征。研究人员表示,对于如何解释结果需要慎重。This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers.
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