2012年12月31日星期一

网易科技频道IT业界新闻: 分析称苹果股价被低估 已具有较大吸引力

网易科技频道IT业界新闻

网易科技频道IT业界新闻

分析称苹果股价被低估 已具有较大吸引力
http://tech.163.com/13/0101/11/8K4ODG6K000915BD.html
Jan 1st 2013, 11:56

网易科技讯 2013年1月1日消息,《福布斯》网站日前发表一篇作者为Darcy Travlos的分析文章,对9月份以来苹果股价下跌的原因进行分析,并指出苹果目前的股价较低,一旦市场的确定性提高,该个股将非常具有吸引力。
以下为文章主要内容:
苹果应该是过去两个月最受关注的股票。我的手机上每几分钟就会弹出一条新的苹果新闻提醒,甚至令我有了苹果新闻审美疲劳。目前对于苹果股价下行的原因有很多争论,但都与该公司的估值无关。有一点已经几乎达成共识的,即苹果股票的价值受低估。以下是苹果从9月份705美元的股价新高累计下跌27%的几个原因。
苹果曾是过去12个月表现最好的个股之一,在9月份触及历史高位705美元,对投资者的回报率达到68%。该股的涨幅比同期的道指、纳斯达克和标普表现超过3倍。投资者,尤其是机构投资者,在这种情况下倾向于锁定收益。正如我此前曾写道的,苹果是很多机构账户的重仓股之一,这些投资者必须逢高减持以维持该基金的分配限制,即使他们认为该股仍然具有吸引力。
700美元附近出现的这波卖盘也可以被解释为巨额股票收益的税收后果。苹果股价在过去一年大幅上涨,曾经买入和持有该股的投资者在兑现收益的时候将支付税收。虽然税率维持平稳,但是"财政悬崖"可能导致股票收益的税率比目前提高5%至9%。因此这些获得大量资本利得的投资者可能进行抛售以维持收益。
当然,这可能解释为什么苹果在700美元的时候遭遇一波卖盘,但是不能解释为什么该股跌至500美元时却并没有投资者入场。可能"财政悬崖的"的暗淡前景可以解释部分原因。尽管纸质媒体广泛地报道苹果股票情况,但是电视媒体不断地向我们播报财政悬崖磋商的最新结果。即使是"财政悬崖"这个词也令投资者希望先找到一些保障。
投资者可能不会避免市场和资本利得税收上调,但是他们将避免不确定性,而这正是"财政悬崖"所导致的——不确定的投资市场。我们此前已经多次目睹,投资者可能不喜欢华盛顿所指定措施的结果,但是投资者可以按照这些措施行事,因为他们知道市场将按照那些规则运行。因此"财政悬崖"的结果可能对美国经济来具有灾难性,投资者未能制定一套策略并予以执行。目前,投资者可能持有资金保持旁观态度,直到"财政悬崖"被解决。
华尔街是另一个对苹果的潜在负面影响。分析师密切关注该股,将目标股价从1000美元下调至740美元,并调低业绩预期,因此对该股产生负面影响。但是,目前对于该公司2014财年的业绩预测仍然高于苹果股价触及新高时所作的预测。尽管如此,740美元的目标股价仍然代表45%的上涨空间,比吉恩·蒙斯特(Gene Munster,Piper Jaffray公司)的目标股价高77%。我之所以关注蒙斯特,因为他是最长期关注苹果股票的分析师之一,并且进行了多项独立研究以支持自己的研究结论。因此,阅读华尔街分析师的报告,可以看出从任何指标来看苹果股票仍然代表非常健康的收益。
如果市场恢复平稳,将发生什么情况?苹果很大可能又经历一个创历史的12月季度。每一个负面的论点记录了苹果之外的数据。华尔街分析师已经下调了对12月这个季度的业绩预期,从而使该公司的业绩必然超过预期。但是,如果参照历史,市场可能对此不以为然,认为这是苹果最后的辉煌,因为很多人都认为苹果已经丧失其创新的优势。
尽管看低苹果的评论者称该公司已经丧失其创新的触觉,但我认为苹果可能在2012年过度创新。该公司推出了3款新iPad,一款新iPhone,一款新iPod,同时升级了全部Mac产品线。作为消费者,我应该购买哪一台"必须拥有的"设备?以前每一个假日,我明确知道自己应该购买哪款苹果产品,因为市场上肯定有一款产品配置了很多新功能,使其成为当之无愧的选择。但是,苹果在今年假日季为所有人推出了一些产品,该策略似乎起到效果,iPhone和iPad Mini的销售速度前所未有。在未来,苹果可能需要放缓其推出产品的速度,并升级产品周期,专注于几款产品,从而突出向消费者进行介绍。

一旦苹果按照以前的策略运营,投资者将开始再次看好该个股。为什么?因为苹果的股价非常便宜。现在,苹果的市盈率(剔除现金)为2014财年每股盈利的46倍。这显示,市场认为苹果将增长6%。在2012财年(刚刚于9月结束),苹果的增速放缓至45%。该公司是平板电脑和智能手机市场的领导者,根据Gartner的预测,平板电脑市场从2012年到2016年将增长210%,而IDC则预测到2016年智能手机市场规模将增长18%。而在PC市场,该公司的增长只有7%,但整体市场却萎缩8%。可以肯定的是,苹果的增长速度会大大超过市场倍值预测的6%,使其成为具有吸引力的投资选择。一旦市场的确定性提高,苹果现在的股价肯定将非常具有吸引力,不过最大的收益通常实在不确定的时候获得的。(楚慎)
本文来源:网易科技报道
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FXfHvl

互联网新闻-新浪科技: 铁道部12306网出现失误 到达时间早于出发时间

互联网新闻-新浪科技

互联网新闻

铁道部12306网出现失误 到达时间早于出发时间
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/12057941115.shtml
Jan 1st 2013, 04:05

铁道部12306网出现坑爹失误 显示到达时间竟早于出发时间
  中国江苏网12月31日讯(记者 王静)除了网站瘫痪,今天铁道部12306网站(http://www.12306.cn)因为一个低级错误,又让网友笑话了一回。记者刚接到热心网友爆料称,自己在12306查询订票的时候,网页显示某趟火车的到达时间竟然要比出发时间还要早两分钟。
  爆料人称,自己想订从江苏常州到无锡的动车,在铁道部网站http://www.12306.cn网页上,输入查询条件,点击"车票查询"之后,却发现网页显示的D3001次列车的"出发时间"和"到达时间"犯了低级错误。"出发时间是18:20,到达时间却是18:18,这不是坑爹吗!"爆料人说。记者随即登陆12306核实,发现D3001列车确实存在该问题,但再继续查询其他列车的信息时,并没有发现此类错误。
  据了解,12306网站由铁道部信息中心和中国铁道科学研究院共同开发,于2011年6月1日正式上线,耗资约3亿元人民币。遗憾的是,从12306订票网站亮相至今,不仅在出行高峰时期网站瘫痪成为家常便饭,而且退款等流程的不畅也引发了网友的各种吐槽。
  网友"@孟飞1990"说:"铁道部售票官网真是会辞旧迎新呀,在2012年年底买火车票给我送分大力,银行钱扣了,可是购票信息确实请付费,打12306说是20个工作日会将购票钱返还到开户银行,国企了不起呀! "
  网友"@斜阳却照暖被窝"更加生气:"12306越来越过分了,今天买了票,网银钱被扣了,但是票没有购买成功,打电话过去,就是让我等,等了一下午,继续电话,还是让我等,说是系统查不到,你花了几个亿,系统查不到!而且票拿不到不算,钱也不给我退,对我说:没办法,你再等。我能骂人吗? "
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

互联网新闻-新浪科技: 愤怒的小鸟和YouTube成2012最热门应用

互联网新闻-新浪科技

互联网新闻

愤怒的小鸟和YouTube成2012最热门应用
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/11447941113.shtml
Jan 1st 2013, 03:44

YouTube成2012最热门应用
  新浪科技讯 北京时间1月1日上午消息,2012年的全年数据显示,《愤怒的小鸟》、Instagram和Facebook仍是下载量最大的应用,但一批全新的明星应用也在逐步崛起。
  根据市场研究公司Flurry的数据,移动用户今年平均每天花2个小时使用移动应用,较去年增长35%。2013年的这一数字还有望继续提升。
  "用户使用应用的方式在2012发生了转变。"移动营销公司Fiksu副总裁克雷格·帕里(Craig Palli)说。他还补充道,今年最大的变化在于,人们越来越愿意用应用来完成各种各样的日常任务。
  社交网络、媒体和娱乐、照片编辑、游戏等类别仍然最受欢迎,YouTube和《愤怒的小鸟》分别成为苹果App Store排名第一的免费和付费应用。
  与此同时,今年新发布的多款应用也纷纷在收入榜中位列前茅。2月发布的iPhone和Android版《你画我猜》(Draw Somthing)很快获得了广泛传播。虽然后来出现下滑,但仍然是Android和iOS设备中下载量第二大的付费应用。
  帕里说:"《你画我猜》取得了巨大成功,LetterPress和ScrambleWithFriends等其他多人猜谜游戏也都广受欢迎。但从很多角度来看,这些应用都从更具革命性的Words With Friends那里获得了灵感。"
  iPhone、Android和Kindle Fire版的音乐探索应用Songza同样在美国和加拿大实现了不俗增长,成为App Store顶级免费应用之一。
  根据应用研究公司Distimo的统计,今年发布的iPad记事本应用Paper同样成为了收入最高的应用之一。该产品还被苹果列为年度iPad应用。
  但帕里认为,真正具有革命意义的是用户越来越愿意用应用来处理日常任务,包括寻找出租车或酒店,甚至付费。"很多用户正在将应用放在首位,而将传统方法放到其次。"他说。
  Uber和Hailo可以帮助用户预订豪华汽车和出租车,AirBnB和HotelTonight则可以寻找住所,这些应用都在2012年进入主流。
  Square等支付应用以及苹果Passbook的推出,都进一步强化了智能手机的智能钱包功能。
  另外,App Store中的应用也都反映在伦敦奥运、飓风桑迪和美国大选等重大事件中,表明用户通过应用了解和参与这些事件的需求正在增加。(书聿)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

互联网新闻-新浪科技: 雅虎股价创2008年8月以来新高

互联网新闻-新浪科技

互联网新闻

雅虎股价创2008年8月以来新高
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/11537941114.shtml
Jan 1st 2013, 03:53

2008年8月以来雅虎股价走势图
  新浪科技讯 北京时间1月1日上午消息,雅虎股票今天在正常交易的情况下报收于19.97美元,回升到自2008年8月以来的最高点,较夏季最低值上涨了大约三分之一,这对雅虎股票持有者可谓是一个久违的欣喜。
  2008年,雅虎股票从最高的29.66美元一举跌至不到10美元,期间曾于8月份在19.97美元左右停留一段时间后。今年,雅虎股票相较夏季最低值上涨了大约三分之一。雅虎新任CEO玛丽莎·梅耶尔(Marissa Mayer),这位来自谷歌的前高管,看起来是给雅虎股票带来了新鲜的刺激因素。在她就任雅虎CEO之前的数年,雅虎一直处于管理层动荡和业务模式过时的窘境。
  雅虎近期通过系列举措表明该公司正重新归于专注,这些动作包括关闭雅虎韩国业务,关闭雅虎中国的音乐服务;在产品执行上也动作频频,包括重新设计雅虎主页Flickr等。
  当然,梅耶尔带给雅虎的可不只是削减业务,她还为雅虎确立了新的愿景:"雅虎将必须成为一个移动为主的公司。"
  一定程度上,投资者们对雅虎当前的改变喜闻乐见,雅虎上升的股票也反应了该公司正得到投资者和支持者的欢迎。不过,雅虎目前的市值仅为公司盈利的6倍,这是一个非常糟糕的表现,还有很大的提升空间。
  好在雅虎总算以一个近年来最良好的势头迈进2013年,该公司在2013年将如何善用这一发展势头是一个有待解决的问题。毫无疑问,梅耶尔入主雅虎高层可改善该公司的人才招聘问题,可预见在以人为本的科技行业,雅虎将再一次与其它主流科技公司处于同一起跑线。
  雅虎既然确立了移动为主的发展路线,那么当下最重要的事是招聘移动工程师,将合适的人才安排到合适的位置去。这一点正是雅虎过去数年来做得不好的地方,有着丰富的谷歌经历的梅耶尔应当能够解决这一问题。
  按今天19.97美元的交易价计算,雅虎市值为234亿美元。(朱飞)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

焦点新闻-新浪科技: 雅虎股价创2008年8月以来新高

焦点新闻-新浪科技

科技焦点新闻

雅虎股价创2008年8月以来新高
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/11537941114.shtml
Jan 1st 2013, 03:53

2008年8月以来雅虎股价走势图
  新浪科技讯 北京时间1月1日上午消息,雅虎股票今天在正常交易的情况下报收于19.97美元,回升到自2008年8月以来的最高点,较夏季最低值上涨了大约三分之一,这对雅虎股票持有者可谓是一个久违的欣喜。
  2008年,雅虎股票从最高的29.66美元一举跌至不到10美元,期间曾于8月份在19.97美元左右停留一段时间后。今年,雅虎股票相较夏季最低值上涨了大约三分之一。雅虎新任CEO玛丽莎·梅耶尔(Marissa Mayer),这位来自谷歌的前高管,看起来是给雅虎股票带来了新鲜的刺激因素。在她就任雅虎CEO之前的数年,雅虎一直处于管理层动荡和业务模式过时的窘境。
  雅虎近期通过系列举措表明该公司正重新归于专注,这些动作包括关闭雅虎韩国业务,关闭雅虎中国的音乐服务;在产品执行上也动作频频,包括重新设计雅虎主页Flickr等。
  当然,梅耶尔带给雅虎的可不只是削减业务,她还为雅虎确立了新的愿景:"雅虎将必须成为一个移动为主的公司。"
  一定程度上,投资者们对雅虎当前的改变喜闻乐见,雅虎上升的股票也反应了该公司正得到投资者和支持者的欢迎。不过,雅虎目前的市值仅为公司盈利的6倍,这是一个非常糟糕的表现,还有很大的提升空间。
  好在雅虎总算以一个近年来最良好的势头迈进2013年,该公司在2013年将如何善用这一发展势头是一个有待解决的问题。毫无疑问,梅耶尔入主雅虎高层可改善该公司的人才招聘问题,可预见在以人为本的科技行业,雅虎将再一次与其它主流科技公司处于同一起跑线。
  雅虎既然确立了移动为主的发展路线,那么当下最重要的事是招聘移动工程师,将合适的人才安排到合适的位置去。这一点正是雅虎过去数年来做得不好的地方,有着丰富的谷歌经历的梅耶尔应当能够解决这一问题。
  按今天19.97美元的交易价计算,雅虎市值为234亿美元。(朱飞)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

焦点新闻-新浪科技: 愤怒的小鸟和YouTube成2012最热门应用

焦点新闻-新浪科技

科技焦点新闻

愤怒的小鸟和YouTube成2012最热门应用
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/11447941113.shtml
Jan 1st 2013, 03:44

YouTube成2012最热门应用
  新浪科技讯 北京时间1月1日上午消息,2012年的全年数据显示,《愤怒的小鸟》、Instagram和Facebook仍是下载量最大的应用,但一批全新的明星应用也在逐步崛起。
  根据市场研究公司Flurry的数据,移动用户今年平均每天花2个小时使用移动应用,较去年增长35%。2013年的这一数字还有望继续提升。
  "用户使用应用的方式在2012发生了转变。"移动营销公司Fiksu副总裁克雷格·帕里(Craig Palli)说。他还补充道,今年最大的变化在于,人们越来越愿意用应用来完成各种各样的日常任务。
  社交网络、媒体和娱乐、照片编辑、游戏等类别仍然最受欢迎,YouTube和《愤怒的小鸟》分别成为苹果App Store排名第一的免费和付费应用。
  与此同时,今年新发布的多款应用也纷纷在收入榜中位列前茅。2月发布的iPhone和Android版《你画我猜》(Draw Somthing)很快获得了广泛传播。虽然后来出现下滑,但仍然是Android和iOS设备中下载量第二大的付费应用。
  帕里说:"《你画我猜》取得了巨大成功,LetterPress和ScrambleWithFriends等其他多人猜谜游戏也都广受欢迎。但从很多角度来看,这些应用都从更具革命性的Words With Friends那里获得了灵感。"
  iPhone、Android和Kindle Fire版的音乐探索应用Songza同样在美国和加拿大实现了不俗增长,成为App Store顶级免费应用之一。
  根据应用研究公司Distimo的统计,今年发布的iPad记事本应用Paper同样成为了收入最高的应用之一。该产品还被苹果列为年度iPad应用。
  但帕里认为,真正具有革命意义的是用户越来越愿意用应用来处理日常任务,包括寻找出租车或酒店,甚至付费。"很多用户正在将应用放在首位,而将传统方法放到其次。"他说。
  Uber和Hailo可以帮助用户预订豪华汽车和出租车,AirBnB和HotelTonight则可以寻找住所,这些应用都在2012年进入主流。
  Square等支付应用以及苹果Passbook的推出,都进一步强化了智能手机的智能钱包功能。
  另外,App Store中的应用也都反映在伦敦奥运、飓风桑迪和美国大选等重大事件中,表明用户通过应用了解和参与这些事件的需求正在增加。(书聿)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

焦点新闻-新浪科技: 铁道部12306网出现失误 到达时间早于出发时间

焦点新闻-新浪科技

科技焦点新闻

铁道部12306网出现失误 到达时间早于出发时间
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/12057941115.shtml
Jan 1st 2013, 04:05

铁道部12306网出现坑爹失误 显示到达时间竟早于出发时间
  中国江苏网12月31日讯(记者 王静)除了网站瘫痪,今天铁道部12306网站(http://www.12306.cn)因为一个低级错误,又让网友笑话了一回。记者刚接到热心网友爆料称,自己在12306查询订票的时候,网页显示某趟火车的到达时间竟然要比出发时间还要早两分钟。
  爆料人称,自己想订从江苏常州到无锡的动车,在铁道部网站http://www.12306.cn网页上,输入查询条件,点击"车票查询"之后,却发现网页显示的D3001次列车的"出发时间"和"到达时间"犯了低级错误。"出发时间是18:20,到达时间却是18:18,这不是坑爹吗!"爆料人说。记者随即登陆12306核实,发现D3001列车确实存在该问题,但再继续查询其他列车的信息时,并没有发现此类错误。
  据了解,12306网站由铁道部信息中心和中国铁道科学研究院共同开发,于2011年6月1日正式上线,耗资约3亿元人民币。遗憾的是,从12306订票网站亮相至今,不仅在出行高峰时期网站瘫痪成为家常便饭,而且退款等流程的不畅也引发了网友的各种吐槽。
  网友"@孟飞1990"说:"铁道部售票官网真是会辞旧迎新呀,在2012年年底买火车票给我送分大力,银行钱扣了,可是购票信息确实请付费,打12306说是20个工作日会将购票钱返还到开户银行,国企了不起呀! "
  网友"@斜阳却照暖被窝"更加生气:"12306越来越过分了,今天买了票,网银钱被扣了,但是票没有购买成功,打电话过去,就是让我等,等了一下午,继续电话,还是让我等,说是系统查不到,你花了几个亿,系统查不到!而且票拿不到不算,钱也不给我退,对我说:没办法,你再等。我能骂人吗? "
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

互联网新闻-新浪科技: 社交新闻网站Reddit去年PV达370亿 UV破4亿

互联网新闻-新浪科技

互联网新闻

社交新闻网站Reddit去年PV达370亿 UV破4亿
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/10447941076.shtml
Jan 1st 2013, 02:44

  新浪科技讯 北京时间1月1日上午消息,美国社交新闻网站Reddit(reddit.com)宣布,该公司2012年的页面浏览量达到370亿,独立用户访问量达到4亿。另外,该网站全年分享的文章总数为3000万篇,总共收到40亿次投票,平均每篇文章约133次。
  Reddit的月页面浏览量于2011年2月首次突破10亿,2011年12月的数字翻了一番。该服务2012年10月的页面浏览量达到38亿,奥巴马连任美国总统当天的页面浏览量和独立用户访问量分别高达440万和160万。
  意料之中的是,奥巴马连任的文章创下历史记录,成为Reddit当年排名第一的文章,页面浏览量超过550万。
  这些数据都反映了Reddit的破纪录增长速度:2012年全年的月均页面浏览量超过30亿。(书聿)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

网易科技频道IT业界新闻: 惠普透露正在评估出售非核心业务

网易科技频道IT业界新闻

网易科技频道IT业界新闻

惠普透露正在评估出售非核心业务
http://tech.163.com/13/0101/10/8K4KMJ4E000915BD.html
Jan 1st 2013, 10:51

网易科技讯 2013年1月1日消息,据彭博社报道,惠普表示,它正在就出售不符合公司目标的业务的可能性进行评估。而在一年多以前,惠普CEO梅格·惠特曼(Meg Whitman)则称她不打算剥离PC部门。
惠普在12月27日提交给美国证券交易委员会(SEC)的文件中表示,"我们还会继续评估剥离可能不再有助于我们实现目标的资产和业务的可能性。"
惠特曼肩负着扭转惠普运营的重任。11月对所收购的软件公司Autonomy减记88亿美元一事,促使华尔街重新呼吁惠普剥特定业务,如PC和打印机,从而实现股东价值。
惠普在监管文件的"风险因素"章节谈及它正进行相关评估,并指出剥离可能也有一些弊端。该公司称,"当我们决定出售资产或者业务时,我们可能会在寻找合适的买家或者替代退出策略上遇到难题,这会使得我们的战略目标延迟实现。"
司法部调查
惠普在文件中还表示,美国司法部已经开始对Autonomy进行调查。惠普指控Autonomy在去年被收购之前会计造假。
14个月前,惠特曼曾声称,她将保留公司的PC业务。其前任李艾科(Leo Apotheker)曾探索剥离该部门的可能性。PC业务去年实现营收357亿美元,占公司总营收的29%。

而惠特曼则选择了统一PC和打印机集团的管理,让执行副总裁托德·布拉德利(Todd Bradley)领导。打印机部门2012财年实现营收245亿美元,占公司总营收的20%。
惠普发言人迈克尔·萨克尔(Michael Thacker)拒绝对监管文件以外的事情发表评论。
惠普在文件中表示,它出售业务的价格或者条款可能不及其预期,另外,"剥离资产对营收增长的影响可能要大于预期。"
惠普股价今天报收于14.25美元,上涨4.2%。该股今年累计下跌了45%。(乐邦)
(本文来源:网易科技报道 ) This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FXfHvl

科技要闻-新浪科技: 三星Tizen手机明年登陆日本市场

科技要闻-新浪科技

科技时代-科技要闻

三星Tizen手机明年登陆日本市场
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/mobile/n/2013-01-01/10227941065.shtml
Jan 1st 2013, 02:22


  DoCoMo是日本最大的移动运营商,同时也是日本唯一不提供苹果iPhone手机的运营商。目前,iOS和Android在日本享有90%的市场份额,不过,DoCoMo已经联手与韩国制造商三星电子,计划在明年向日本市场提供开源的Tizen智能手机。
  今年早些时候,有传言称,三星将于明年2月份开始生产Tizen手机,同时在2月巴塞罗那MWC 2013大会上发布并展示这款手机。
  外界认为,三星有理由采用安卓之外的操作系统,因为谷歌Nexus智能手机以及准备和摩托罗拉联合研发的"X"手机正在蚕食三星手机市场份额。Tizen操作系统基于Linux,最初是由三星开发,英特尔赞助,用来更换MeeGo操作系统。
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/Cjnnlk

焦点新闻-新浪科技: 谷歌转变策略:借应用由内而外打击苹果

焦点新闻-新浪科技

科技焦点新闻

谷歌转变策略:借应用由内而外打击苹果
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/10167941058.shtml
Jan 1st 2013, 02:16

  导语:美国科技博客BusinessInsider今天撰文称,谷歌已经在移动大战中调整了单纯借助Android系统对抗苹果iOS的方式,开始通过优秀的谷歌应用取代苹果官方应用,希望"由内而外"打击苹果。
  以下为文章全文:
  多年以来,谷歌一直在借助廉价甚至免费的Android手机,与苹果争夺智能手机市场份额。现在,谷歌又开始采取全新的移动市场渗透战略。
  我们暂且称之为"蠕虫战略",因为谷歌正在从内部打击苹果。
  过去6个月间,谷歌开始系统性地推出各种iOS应用,逐步取代功能相似的苹果官方应用:
  ——7月,谷歌发布Chrome for iPhone,取代Safari。
  ——10月,谷歌推出搜索应用,利用内置的语音搜索功能与Siri竞争。
  ——12月,谷歌发布了地图应用,取代苹果地图,还大幅升级了Gmail应用,以取代苹果的Mail应用。
  ——谷歌还推出了独立YouTube应用,而苹果此前刚刚在新版iOS中移除了预装的YouTube应用。
  谷歌并不准备就此罢休。事实上,该公司正在向iOS领域投入更多资源。
  美国科技博客9to5Mac编辑杰克·史密斯(Jake Smith)指出,谷歌已经发布了一条广告,希望招募iOS开发者,以便"做一些又酷又有意义的事情"。
  该广告链接到谷歌内部的招聘网站,内容是对谷歌iOS开发者肯·邦格特(Ken Bongort)的一次采访。这篇采访摘要的题目是:"等等,谷歌还有iOS移动应用团队?"
  邦格特在采访中提到了谷歌最近在iOS平台上发布的各种应用,最后总结说:"不用说,为iOS平台上的所有谷歌应用开发并设计全新的体验存在着相似的机会。"
  谷歌的策略的确起到了作用。
  我们身边就有一个活生生的例子:BusinessInsider电子产品编辑史蒂夫·科瓦奇(Steve Kowach)表示,他几乎将所有的苹果iOS应用都放到了一个隐藏文件夹下,优先选择使用谷歌或其他企业开发的应用。
  AllThingsD的利兹·加尼斯(Liz Gannes)表示,她2012年几乎停用了所有苹果iOS应用,主要原因是谷歌陆续推出了iOS应用。她说:"我发现自己通常都会使用谷歌iOS应用。我现在使用谷歌地图代替苹果地图,用Chrome代替Safari,用Gmail代替Mail。我把这三款应用放到主屏上,代替了苹果自主开发的应用。"
  她还补充道:"需要强调的是,我既不是苹果的粉丝,也不是谷歌的拥趸——我赞赏谷歌的移动软件,但我最主要的手机仍然是iPhone。我认为iOS是一款非常优秀的操作系统,但谷歌的应用却更符合我的需求,包括一些智能手机最重要、最基础的功能。"
  另外,还有一些统计数据也表明,谷歌这种由内而外的策略的确收到成效。
  市场研究公司AppData的数据显示,排名第一和第二的免费iPhone应用分别是YouTube和谷歌地图。
  这些趋势必然令苹果高管感到忧虑。
  有报道称,由于谷歌地图博得满堂彩,加之用户急于用该服务替换苹果地图,令苹果高管"心似火烧"。这完全在意料之中。在苹果iOS主管斯科特·福斯特(Scott Forstall)拒绝就地图服务道歉后,苹果CEO蒂姆·库克(Tim Cook)便解雇了他。
  与此同时,这一趋势却令谷歌高管欢欣鼓舞。
  当苹果2008年推出App Store时,便威胁要颠覆谷歌最重要的业务:搜索。
  如果按照苹果的设想,世界将变成这样:
  ——企业将所有资源都投向应用开发领域,以便能够提升App Store中的曝光率,而不再建设谷歌搜索赖以生存的网页。
  ——用户会直接使用非谷歌应用解决搜索问题,包括到哪里购物,买什么东西。
  ——于是,为谷歌贡献了95%收入的搜索广告的价值将大幅萎缩。
  但事实上,真正的发展过程中,整个世界分化成了两类人:一类是Android用户,他们被谷歌搜索包围;另外一类是iPhone用户,他们都在下载谷歌应用——这些应用都将谷歌搜索作为主要功能来提供。(书聿)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

焦点新闻-新浪科技: 社交新闻网站Reddit去年PV达370亿 UV破4亿

焦点新闻-新浪科技

科技焦点新闻

社交新闻网站Reddit去年PV达370亿 UV破4亿
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/10447941076.shtml
Jan 1st 2013, 02:44

  新浪科技讯 北京时间1月1日上午消息,美国社交新闻网站Reddit(reddit.com)宣布,该公司2012年的页面浏览量达到370亿,独立用户访问量达到4亿。另外,该网站全年分享的文章总数为3000万篇,总共收到40亿次投票,平均每篇文章约133次。
  Reddit的月页面浏览量于2011年2月首次突破10亿,2011年12月的数字翻了一番。该服务2012年10月的页面浏览量达到38亿,奥巴马连任美国总统当天的页面浏览量和独立用户访问量分别高达440万和160万。
  意料之中的是,奥巴马连任的文章创下历史记录,成为Reddit当年排名第一的文章,页面浏览量超过550万。
  这些数据都反映了Reddit的破纪录增长速度:2012年全年的月均页面浏览量超过30亿。(书聿)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

Solidot: 大熊猫血液可能是对抗超级细菌的强大武器

Solidot

奇客的资讯,重要的东西

大熊猫血液可能是对抗超级细菌的强大武器
http://solidot.org.feedsportal.com/c/33236/f/556826/s/2716ce22/l/0L0Ssolidot0Borg0Cstory0Dsid0F32915/story01.htm
Jan 1st 2013, 01:56

科学家发现,拯救大熊猫还有更大的意义,它们的血流中能生出强有力的抗菌物质,杀死细菌和真菌。中国研究人员在分析大熊猫的DNA时发现,这种化合物质被称为抗菌肽-AM,由大熊猫免疫系统释放,防止它们在野生环境中生活时受感染。抗菌肽-AM能在1小时内杀死细菌,而人类制造的抗菌素,则需要花6个小时以上才能杀死细菌。幸运的是,科学家不必依赖大熊猫来获取这一物质,他们能在实验室里利用基因编码人工合成。负责这一研究的中国南京农业大学生命科学院的严修文博士说,这意味着制造对付包括普通细菌和真菌、以及具有抗药性的细菌在内的强力抗菌素的可能性。 由于具有抗药性的超级细菌越来越普遍,制造新品种的具有更大抗菌能力的药物的需求也就更急迫。

This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/jPbdSR

互联网新闻-新浪科技: 谷歌转变策略:借应用由内而外打击苹果

互联网新闻-新浪科技

互联网新闻

谷歌转变策略:借应用由内而外打击苹果
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/10167941058.shtml
Jan 1st 2013, 02:16

  导语:美国科技博客BusinessInsider今天撰文称,谷歌已经在移动大战中调整了单纯借助Android系统对抗苹果iOS的方式,开始通过优秀的谷歌应用取代苹果官方应用,希望"由内而外"打击苹果。
  以下为文章全文:
  多年以来,谷歌一直在借助廉价甚至免费的Android手机,与苹果争夺智能手机市场份额。现在,谷歌又开始采取全新的移动市场渗透战略。
  我们暂且称之为"蠕虫战略",因为谷歌正在从内部打击苹果。
  过去6个月间,谷歌开始系统性地推出各种iOS应用,逐步取代功能相似的苹果官方应用:
  ——7月,谷歌发布Chrome for iPhone,取代Safari。
  ——10月,谷歌推出搜索应用,利用内置的语音搜索功能与Siri竞争。
  ——12月,谷歌发布了地图应用,取代苹果地图,还大幅升级了Gmail应用,以取代苹果的Mail应用。
  ——谷歌还推出了独立YouTube应用,而苹果此前刚刚在新版iOS中移除了预装的YouTube应用。
  谷歌并不准备就此罢休。事实上,该公司正在向iOS领域投入更多资源。
  美国科技博客9to5Mac编辑杰克·史密斯(Jake Smith)指出,谷歌已经发布了一条广告,希望招募iOS开发者,以便"做一些又酷又有意义的事情"。
  该广告链接到谷歌内部的招聘网站,内容是对谷歌iOS开发者肯·邦格特(Ken Bongort)的一次采访。这篇采访摘要的题目是:"等等,谷歌还有iOS移动应用团队?"
  邦格特在采访中提到了谷歌最近在iOS平台上发布的各种应用,最后总结说:"不用说,为iOS平台上的所有谷歌应用开发并设计全新的体验存在着相似的机会。"
  谷歌的策略的确起到了作用。
  我们身边就有一个活生生的例子:BusinessInsider电子产品编辑史蒂夫·科瓦奇(Steve Kowach)表示,他几乎将所有的苹果iOS应用都放到了一个隐藏文件夹下,优先选择使用谷歌或其他企业开发的应用。
  AllThingsD的利兹·加尼斯(Liz Gannes)表示,她2012年几乎停用了所有苹果iOS应用,主要原因是谷歌陆续推出了iOS应用。她说:"我发现自己通常都会使用谷歌iOS应用。我现在使用谷歌地图代替苹果地图,用Chrome代替Safari,用Gmail代替Mail。我把这三款应用放到主屏上,代替了苹果自主开发的应用。"
  她还补充道:"需要强调的是,我既不是苹果的粉丝,也不是谷歌的拥趸——我赞赏谷歌的移动软件,但我最主要的手机仍然是iPhone。我认为iOS是一款非常优秀的操作系统,但谷歌的应用却更符合我的需求,包括一些智能手机最重要、最基础的功能。"
  另外,还有一些统计数据也表明,谷歌这种由内而外的策略的确收到成效。
  市场研究公司AppData的数据显示,排名第一和第二的免费iPhone应用分别是YouTube和谷歌地图。
  这些趋势必然令苹果高管感到忧虑。
  有报道称,由于谷歌地图博得满堂彩,加之用户急于用该服务替换苹果地图,令苹果高管"心似火烧"。这完全在意料之中。在苹果iOS主管斯科特·福斯特(Scott Forstall)拒绝就地图服务道歉后,苹果CEO蒂姆·库克(Tim Cook)便解雇了他。
  与此同时,这一趋势却令谷歌高管欢欣鼓舞。
  当苹果2008年推出App Store时,便威胁要颠覆谷歌最重要的业务:搜索。
  如果按照苹果的设想,世界将变成这样:
  ——企业将所有资源都投向应用开发领域,以便能够提升App Store中的曝光率,而不再建设谷歌搜索赖以生存的网页。
  ——用户会直接使用非谷歌应用解决搜索问题,包括到哪里购物,买什么东西。
  ——于是,为谷歌贡献了95%收入的搜索广告的价值将大幅萎缩。
  但事实上,真正的发展过程中,整个世界分化成了两类人:一类是Android用户,他们被谷歌搜索包围;另外一类是iPhone用户,他们都在下载谷歌应用——这些应用都将谷歌搜索作为主要功能来提供。(书聿)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

手机资讯-新浪科技: 三星Tizen手机明年登陆日本市场

手机资讯-新浪科技

手机资讯

三星Tizen手机明年登陆日本市场
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/mobile/n/2013-01-01/10227941065.shtml
Jan 1st 2013, 02:22


  DoCoMo是日本最大的移动运营商,同时也是日本唯一不提供苹果iPhone手机的运营商。目前,iOS和Android在日本享有90%的市场份额,不过,DoCoMo已经联手与韩国制造商三星电子,计划在明年向日本市场提供开源的Tizen智能手机。
  今年早些时候,有传言称,三星将于明年2月份开始生产Tizen手机,同时在2月巴塞罗那MWC 2013大会上发布并展示这款手机。
  外界认为,三星有理由采用安卓之外的操作系统,因为谷歌Nexus智能手机以及准备和摩托罗拉联合研发的"X"手机正在蚕食三星手机市场份额。Tizen操作系统基于Linux,最初是由三星开发,英特尔赞助,用来更换MeeGo操作系统。
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/twQHL8

网易科技频道IT业界新闻: 微软发布补丁 修复低版本IE最新安全漏洞

网易科技频道IT业界新闻

网易科技频道IT业界新闻

微软发布补丁 修复低版本IE最新安全漏洞
http://tech.163.com/13/0101/10/8K4I2IGR000915BD.html
Jan 1st 2013, 10:05



上周末,软件安全公司FireEye公布了存在于微软IE 6/7/8浏览器中的一个新0day漏洞。今日,微软正式针对该漏洞发布了"Fix it"快速修复补丁,并建议所有使用上述三款IE浏览器的用户及时进行更新。

微软表示,"Fix it"是一款一键式修复补丁,它可以有效阻止黑客利用0day漏洞对浏览器所发起的攻击,而且不会影响浏览器的网页浏览性能,同时,用户在安装完该补丁之后也无需重新启动计算机。
另外,微软还表示将会继续开发完整的安全更新补丁来彻底封堵漏洞并阻止其工作,但并未公布具体的发布时间。
据此前消息,微软IE 6/7/8浏览器的最新0day漏洞最早被发现于黑客针对美国外交关系委员会网站的攻击行为中,黑客通过该漏洞利用JavaScript恶意代码调用Adobe Flash文件对IE浏览器实施Heap Spray攻击,目前该漏洞已被证明不会影响微软IE 9/10浏览器。
(本文来源:驱动之家MyDrivers 作者:小路) This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FXfHvl

焦点新闻-新浪科技: 亚马逊就云计算业务故障道歉:未提Netflix

焦点新闻-新浪科技

科技焦点新闻

亚马逊就云计算业务故障道歉:未提Netflix
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/09147940981.shtml
Jan 1st 2013, 01:14

  新浪科技讯 北京时间1月1日上午消息,亚马逊上周六在官方网站上发布了一封长信,对该公司的云计算服务在圣诞前夜的崩溃做出了技术解释,并表达了歉意。虽然这一故障导致Netflix的服务宕机,但亚马逊在道歉信中却对这家竞争对手只字未提。
  这一故障对整个圣诞前夜的服务造成了影响,圣诞节当天的部分时段也受到了波及。
  Netflix的宕机最为引人关注,但该公司并非唯一一家受此影响的企业。亚马逊的故障还影响到其他客户,包括Salesforce.com的Heroku。而由于Heroku本身也是一家云计算服务提供商,并托管了其他公司的应用,导致亚马逊的故障影响到了各种类型的公司。
  然而,亚马逊自家的流媒体电影服务Amazon Instant Video却并未受到影响,该服务与Netflix存在竞争关系。
  亚马逊在上周六的那封长信中解释称,这起故障的源头始于一个人为错误:有一位员工不小心删除了一些非常重要的数据。但亚马逊承诺今后不会再出现同样的错误。
  亚马逊说:"我们深表歉意。我们深知自己的服务对客户的业务有多么重要,我们也深知此次故障对部分客户来说非常不合时宜。我们会尽一切努力从中吸取教训,进一步改善ELB服务。"
  但在圣诞前夜观看电影是一项重要的传统,因此Netflix的宕机引发了巨大反响。Netflix随后在官方Twitter账号中发表了一连串声明,将错误归咎于亚马逊。但也有业内人士认为,Netflix完全依赖于亚马逊的做法并非明智之举。
  Netflix CEO里德·哈斯汀斯(Reed Hastings)上月表示,到2013年底,他希望Netflix能将所有服务都转移到亚马逊云计算基础设施中,这样一来,Netflix就将成为亚马逊云计算服务的最大客户。(书聿)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

焦点新闻-新浪科技: 惠普或出售业绩未达标业务部门

焦点新闻-新浪科技

科技焦点新闻

惠普或出售业绩未达标业务部门
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/it/2013-01-01/09407941024.shtml
Jan 1st 2013, 01:40

[unable to retrieve full-text content]  新浪科技讯 北京时间1月1日早间消息,惠普表示,该公司正在对未能完成目标的业务部门进行评估,有可能会出售这些部门。在一年多以前,惠普CEO梅格・惠特曼(Meg Whitman)称其不计划分拆公司旗下PC部门。

  惠普在10月27日向美国证券交易委员会(SEC)提交的10-K文件中称:"....



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

网易科技频道要闻: 国家邮政局回应快递野蛮分拣:依法处理涉事企业

网易科技频道要闻

网易科技频道要闻

国家邮政局回应快递野蛮分拣:依法处理涉事企业
http://tech.163.com/12/1231/22/8K38O4GH00094MOK.html
Dec 31st 2012, 21:49

中新网12月31日电 据国家邮政局网站消息,关于此前媒体关于快递企业内件丢失、野蛮分拣、霸王条款的报道,国家邮政局日前发布通知,称有关省(市)邮政管理局要对涉嫌违规的企业进行约谈和依法严肃处理。
国家邮政局12月31日发出通知,要求各省(区、市)邮政管理局切实加强对快递服务的监督管理,提高快递服务质量。通知要求,各地邮政管理部门要采取措施督导辖区内快递企业严格执行有关法律法规和《快递服务》标准、《快递业务操作指导规范》等规定和要求,认真履行服务承诺,努力提升服务质量。有关省(市)邮政管理局要督导快递企业总部加强自身品牌网络的管理工作,在所属公司和营业网点中要严格执行统一的服务标准、操作规范和操作流程,严禁出现野蛮分拣和抛扔、踩踏快件等违规行为。
通知指出,要结合开展快递服务质量专项整治活动,严肃查处快递企业损害消费者合法权益的行为。对消费者申诉中反映快件延误、快件丢失短少、快件损毁、收投服务等突出问题,以及媒体曝光的典型案例进行重点查处,要充分发挥专项整治活动的作用,推动企业加强管理,改善服务,提高服务质量。
对未经许可违法经营快递业务,以及通过加盟、委托、承包等形式超出许可范围违法经营快递业务的行为,要依法严厉查处。要加强对快递企业持续符合经营许可条件的检查,要综合运用许可变更、年度报告、市场退出等手段,对不能持续符合许可条件、快递服务质量低劣,严重损害消费者利益的快递企业,依法予以处理。

通知要求,各地快递行业协会要积极发挥行业自律作用,切实落实行业自律公约。要通过树立典型企业、解剖问题企业,引导快递行业加强自律,推动快递企业强化管理。
2013年元旦和春节即将来临,国家邮政局要求各地邮政管理部门、快递行业协会要督导快递企业,认真做好双节期间的快递服务,严格履行服务承诺,保障快件揽收、投递工作的正常进行,为消费者提供满意的快递服务。(中新网财经频道)
本文来源:中国新闻网
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/g75ZtT

互联网新闻-新浪科技: 亚马逊就云计算业务故障道歉:未提Netflix

互联网新闻-新浪科技

互联网新闻

亚马逊就云计算业务故障道歉:未提Netflix
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/09147940981.shtml
Jan 1st 2013, 01:14

[unable to retrieve full-text content]  新浪科技讯 北京时间1月1日上午消息,亚马逊上周六在官方网站上发布了一封长信,对该公司的云计算服务在圣诞前夜的崩溃做出了技术解释,并表达了歉意。虽然这一故障导致Netflix的服务宕机,但亚马逊在道歉信中却对这家竞争对手只字未提。

  这一故障对整个圣诞前夜的服务....



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

互联网新闻-新浪科技: Zynga已关闭11款游戏:将转换业务重心

互联网新闻-新浪科技

互联网新闻

Zynga已关闭11款游戏:将转换业务重心
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/08427940918.shtml
Jan 1st 2013, 00:42

[unable to retrieve full-text content]  新浪科技讯 北京时间1月1日上午消息,社交游戏公司Zynga周一确认称,该公司计划关闭的13款游戏中已有11款被关闭,其中最新关闭的一款是《Petville》。

  Zynga在今年10月称其将关闭13款表现不佳的游戏,此前该公司发出警告称,由于Facebook平台上一度流行的Zynga游戏面临....



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

科技要闻-新浪科技: 电话订火车票今起全国通取 方便低收入旅客

科技要闻-新浪科技

科技时代-科技要闻

电话订火车票今起全国通取 方便低收入旅客
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06187940622.shtml
Dec 31st 2012, 22:18

  新京报讯 (记者刘春瑞)从今天起,通过电话预订的火车票可全国通取,取票时间延长12小时。1月4日起,互联网、电话订票预售期调整为20天(含当天)。
  电话订票
  取票延长12个小时
  记者从铁道部获悉,自2013年1月1日起,通过电话预订车票的旅客可凭订票时乘车人有效身份证件,到全国任一车站窗口或代售点换取已订车票,实现电话订票全国通取。
  同时,电话订票的取票时间延长12个小时,即:当日12:00前已订车票于第二日12:00前取有效;当日12:00后已订车票于第二日24:00前取有效。
  此前,电话预订的车票只能在发车站所在的铁路局管内取票。
  预售方式
  每小时均有新票起售
  自2013年1月1日起,互联网、电话订票预订第12天车票的起售时间由原来4个节点调整为10个节点,即8:00~18:00(14:00除外)期间每小时均有部分新票起售,所有动车组列车(C、D、G字头车次)车票统一于11:00起售。具体起售时间详见各车站公告,或登录www.12306.cn网站首页"最新动态"栏查询。
  记者查询12306网站,北京西站发车普通客车车票8:00起售,北京站和北京北站发车普通客车车票10:00起售,北京南站11:00起售。
  预售期限
  预售期延长至20天
  自2013年1月4日起,火车票互联网、电话订票预售期延长至20天(含当日),预订第20天车票的起售时间仍为10个节点,代售点和车站部分售票窗口预售期延长至18天(含当日)。
  铁路部门提醒广大旅客注意电话订票取票时间和范围、互联网和电话订票起售时间、火车票预售期的变化,合理安排好购票计划。
  ■ 专家观点
  举措尤其方便低收入旅客
  北京交通大学教授赵坚认为,电话订票全国通取并延长时间,主要方便了农民工。因为网络购票对农民工来说不是很方便,农民工大多采用电话订票的方式。可以异地取票后,大大方便了农民工取返程票。
  对于延长的预售期,赵坚表示,延长的时间越长越好,对于铁道部来说,可比之前更早提前知道不同线路的需求,便于行车组织,在哪条线上加临客。对于旅客来说,可以更提前订票,有计划出行。对农民工等低收入群体来说,计划的时间比较长,而商务出行不太可能计划太早出行。这些举措都是比较好的,更方便旅客,尤其是低收入旅客。
  新京报记者 刘春瑞
  ■ 团体订票
  今起外来务工者可订团体火车票
  集中办理时间:1月1日-1月15日;一次订票数量需在6张及以上
  新京报讯 (记者汤旸)今起至1月15日,北京市将办理1月26日至2月8日离京、2月13日至2月28日回京的来京务工人员团体火车票。
  四大火车站设办理专口
  北京市交通委昨日表示,今年全市外来务工人员团体往返火车票计划购票,将首次试点互联网集中办理方式。此次集中办理在1月1日至1月15日期间进行,完成企业资质认证、证书发放,订单提交工作。1月18日前完成制票、取票工作。
  目前,北京站、北京西站、北京南站、北京北站设置了专口,办理来京务工人员团体往返票互联网订单的集中受理工作,受理时间为每日上午9:00至11:30;下午13:00至16:00。
  据介绍,一次订票数量需在6张及以上。
  务工者可预订长途客票
  1月17日至2月1日,来京务工人员可预订团体长途客票;1月21日至2月5日,来京务工人员可直接购买团体长途客票。此外,来京务工人员还可登录北京省际客运信息网(www.e2go.com.cn)购买长途客票。
  ■ 链接
  务工者预订团体火车票办法
  主要对象:来京务工人员订团体火车票
  出行时间:1月26日-2月8日离京;2月13日-2月28日回京。
  办理地点:北京站售票大厅3、4号窗口;北京西站北广场东售票厅19、20号窗口,南广场西售票厅2号窗口;北京南站高架3号售票厅,地下一层5号售票厅;北京北站一层售票厅5号窗口。
  办理时间:每日9:00-11:30;13:00-16:00。
  提供材料:企业营业执照复印件;企业法人代表的身份证复印件;办票人身份证复印件,联系方式,包括电话、电子邮箱。
  办理流程:订票单位准备所需材料及承诺书,到车站互联网办理专口提交申请;车站经过认证后,将订票单位的单位名称,订票人信息和联系方式报路局客票所,进行网上提交订单授权证书发放,证书由路局客票所传真给办理站,由办理站发放给相关企业;订票负责人进行网上订票;制票完成后,由受理站通知企业取票、付款。取票时,取票人应与企业办票人相符。
  订票单内容包括乘车日期、车次、到站、张数、同时携带乘车人的有效证件复印件。订票单一式三份,两份交受理车站,一份由订票单位留存,作为取票凭证。
  备注:一次订票数量需在6张及以上。
  ■ 数说
  春运北京加开75列临客列车
  2013年北京铁路局春运临客方案昨日出台,北京铁路局共加开75列临客。具体临客开行日期、车次情况、列车到发时刻,请登录www.12306.cn查询或详见各车站公告。
  记者从北京西站获悉,元旦假日期间,北京西站将以中短途探亲流、农民工客流为主。预计"元旦"小长假2012年12月31日至2013年1月3日4天内,北京西站将发送旅客55.2万人,日均13.8万人。客流高峰日为12月31日,预计发送旅客15万人。旅客出行目的地主要集中在西安、太原、郑州、武昌、石家庄、邯郸等方向。
  新京报记者 刘春瑞
  ■ 公路
  13省份长途客运试点接驳运输
  1月20日起,试点客车不受凌晨2时-5时停运制约,可夜间通行
  新京报讯 (记者汤旸)交通运输部昨日发布通知,1月20日起,北京、上海等13个省份将试点长途客运接驳运输,携带有效标识和《长途客运接驳运输行车单》的试点客车,不受凌晨2时至5时停止运行的规定,允许夜间通行,但驾驶员需在接驳点换人继续执行客运任务。
  试点完善后向全国推广
  所谓长途客运接驳运输,是指通过在客车运行途中选择合适的地点,实施驾驶员停车换人、落地休息,或换车换人,由在接驳点上休息等待的驾驶员上车驾驶,继续执行客运任务的运输组织方式。
  交通运输部表示,长途客运接驳运输既可以使驾驶员得到良好的休息,防止疲劳驾驶,又可以避免客车夜间停驶产生的诸多问题。
  13个试点省份包括北京、上海、江苏、浙江、安徽、福建、山东、河南、广东、广西、四川、重庆、贵州。待试点工作开展一段时间后,再总结完善向全国推广。
  试点卧铺车应装安全门
  每个试点省份可选择不超过3家骨干客运企业进行试点。试点企业应当在2012年内未发生较大责任事故,企业所属的长途客运车辆全部安装了符合标准的车辆卫星定位装置。
  企业应选用装有车载视频监控装置的客车参加接驳运输试点,参加试点的卧铺客车应具有安全门或外推式安全车窗。
  接驳点不允许新增旅客
  申请接驳运输试点的客运班线原则上应为主要在高速公路上运行的800公里以上长途客运线路。试点线路的起讫点限于参与试点的省份,但线路可以途经其他省份。
  接驳点应当设置在高速公路服务区或高速公路出口附近,应有固定场所,满足驾驶员食宿、车辆临时停靠等基本要求。
  除与经批准的客运站点重合的接驳点外,接驳点不允许增加新的旅客。
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/Cjnnlk

焦点新闻-新浪科技: 维多利亚时代怪异发明:狗踩踏板式缝纫机

焦点新闻-新浪科技

科技焦点新闻

维多利亚时代怪异发明:狗踩踏板式缝纫机
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/d/2013-01-01/08327940906.shtml
Jan 1st 2013, 00:32

1882年著作《流行科学娱乐》刊登的一幅图片,展示了法国商人M-理查德发明的狗动力缝纫机
  1882年出版的著作《流行科学娱乐》描述了这种狗动力缝纫机,将其称之为"一项充分利用动物体重和力量的革命性发明"
  新浪科技讯 北京时间1月1日消息,据国外媒体报道,在实现机动化和数字化之前,我们一直让动物帮助我们完成日常工作。虽然马和牛是最常见的动物助手,但维多利亚时代的一名发明家却独辟蹊径,发明了由狗狗驱动的缝纫机,利用狗狗踩踏板转动缝纫机的轮子。这位发明家就是法国商人M-理查德,发明狗动力缝纫机的目的是拯救其巴黎公司的缝纫女工的脆弱双手。
  1882年出版的著作《流行科学娱乐》(Popular Scientific Recreations)描述了这种狗动力缝纫机,将其称之为"一项充分利用动物体重和力量的革命性发明"。在《流行科学娱乐》刊登的图像中,一条狗被放在旋转轮上方的箱子里面,通过踩踏板驱动轮子转动。根据这本书的描述,箱子内放有一个倾斜台,迫使狗狗爬坡,进而产生动力。这项发明的基本原理是利用狗狗的静负载产生的力量。狗是一种非常好动的动物,能够确保轮子始终处于转动状态。
  在发现缝纫机对工人健康产生不利影响之后,理查德产生了打造这一发明的想法,借助狗这种"四脚发动机"的力量解放缝纫女工,进而避免她们因使用缝纫机出现健康损伤。《流行科学娱乐》称这是一种具有成本效益的缝纫机。此外,理查德也不忘保证狗狗的福利,为箱子前方安装一个支架,上面放上一个水碗。(杨孝文)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

焦点新闻-新浪科技: 国家邮政局回应快递野蛮分拣:依法严肃处理

焦点新闻-新浪科技

科技焦点新闻

国家邮政局回应快递野蛮分拣:依法严肃处理
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/09067940979.shtml
Jan 1st 2013, 01:06

  中新网12月31日电 据国家邮政局网站消息,关于此前媒体关于快递企业内件丢失、野蛮分拣、霸王条款的报道,国家邮政局日前发布通知,称有关省(市)邮政管理局要对涉嫌违规的企业进行约谈和依法严肃处理。
  国家邮政局12月31日发出通知,要求各省(区、市)邮政管理局切实加强对快递服务的监督管理,提高快递服务质量。通知要求,各地邮政管理部门要采取措施督导辖区内快递企业严格执行有关法律法规和《快递服务》标准、《快递业务操作指导规范》等规定和要求,认真履行服务承诺,努力提升服务质量。有关省(市)邮政管理局要督导快递企业总部加强自身品牌网络的管理工作,在所属公司和营业网点中要严格执行统一的服务标准、操作规范和操作流程,严禁出现野蛮分拣和抛扔、踩踏快件等违规行为。
  通知指出,要结合开展快递服务质量专项整治活动,严肃查处快递企业损害消费者合法权益的行为。对消费者申诉中反映快件延误、快件丢失短少、快件损毁、收投服务等突出问题,以及媒体曝光的典型案例进行重点查处,要充分发挥专项整治活动的作用,推动企业加强管理,改善服务,提高服务质量。
  对未经许可违法经营快递业务,以及通过加盟、委托、承包等形式超出许可范围违法经营快递业务的行为,要依法严厉查处。要加强对快递企业持续符合经营许可条件的检查,要综合运用许可变更、年度报告、市场退出等手段,对不能持续符合许可条件、快递服务质量低劣,严重损害消费者利益的快递企业,依法予以处理。
  通知要求,各地快递行业协会要积极发挥行业自律作用,切实落实行业自律公约。要通过树立典型企业、解剖问题企业,引导快递行业加强自律,推动快递企业强化管理。
  2013年元旦和春节即将来临,国家邮政局要求各地邮政管理部门、快递行业协会要督导快递企业,认真做好双节期间的快递服务,严格履行服务承诺,保障快件揽收、投递工作的正常进行,为消费者提供满意的快递服务。(中新网财经频道)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

焦点新闻-新浪科技: Zynga已关闭11款游戏:将转换业务重心

焦点新闻-新浪科技

科技焦点新闻

Zynga已关闭11款游戏:将转换业务重心
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/08427940918.shtml
Jan 1st 2013, 00:42

  新浪科技讯 北京时间1月1日上午消息,社交游戏公司Zynga周一确认称,该公司计划关闭的13款游戏中已有11款被关闭,其中最新关闭的一款是《Petville》。
  Zynga在今年10月称其将关闭13款表现不佳的游戏,此前该公司发出警告称,由于Facebook平台上一度流行的Zynga游戏面临着玩家大批流失的困境,其营收增长速度正在放缓,并因此大幅下调了全年的业绩预期。Zynga宣布,《Petville》这款游戏已经在两个星期以前关闭,所有11款已被关闭的游戏都是在12月关闭的,这些游戏要么完全被关闭,要么不再接受新玩家,如《黑手党2》(Mafia Wars 2)、《黑夜战记》(Vampire Wars)、《梦境森林》(ForestVille)和《FishVille》等。
  Zynga在《Petville》的Facebook页面上向玩家称:"在关闭《Petville》以后,我们鼓励玩家去玩其他的Zynga游戏,如《Castleville》、《Chefville,》、《Farmville 2》、《黑手党》和《Yoville》等。《Petville》的玩家可在这些游戏中获得一次性免费赠送的虚拟物品奖励包。"
  《Petville》在Facebook上被点"赞"的次数为750万次,但据AppData统计的数据显示,这款游戏的每日活跃用户人数仅为6万人。大约有1260名用户在这款游戏的Facebaook页面上留言,其中一些用户对这款游戏被关闭表示遗憾。Zynga表示,该公司将转换业务重心,将重点放在移动游戏的增长机会上。本月Zynga还在内华达州初步申请试运营真实的博彩游戏,希望这一真实游戏市场能抵消《FarmVille》等游戏营收下滑所带来的不利影响。(唐风)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

ScienceDaily: Latest Science News: Direct evidence for receptor's role in synapse development

ScienceDaily: Latest Science News

Breaking science news and articles on global warming, extrasolar planets, stem cells, bird flu, autism, nanotechnology, dinosaurs, evolution -- the latest discoveries in astronomy, anthropology, biology, chemistry, climate and environment, computers, engineering, health and medicine, math, physics, psychology, technology, and more -- from the world's leading universities and research organizations.

Direct evidence for receptor's role in synapse development
http://feeds.sciencedaily.com/~r/sciencedaily/~3/Ilph_sjEjzg/121231161049.htm
Dec 31st 2012, 21:10

Dec. 31, 2012 — Jackson Laboratory researchers led by Associate Professor Zhong-wei Zhang, Ph.D., have provided direct evidence that a specific neurotransmitter receptor is vital to the process of pruning synapses in the brains of newborn mammals.

Faulty pruning at this early developmental stage is implicated in autism-spectrum disorders and schizophrenia. The definitive evidence for N-methyl-D-aspartate receptor (NMDAR) in pruning has eluded researchers until now, but in research published in the Proceedings of the National Academy of Sciences, Zhang's lab had serendipitous help in the form of a mouse model containing brain cells lacking NMDAR side-by-side with cells containing the receptor.
Soon after birth, mammals' brains undergo significant development and change. Initially, large numbers of synapses form between neurons. Then, in response to stimuli, the synaptic connections are refined -- some synapses are strengthened and others eliminated, or pruned.
In most synapses, glutamate serves as the neurotransmitter, and NMDAR, a major type of post-synaptic glutamate receptor, was previously known to play an important role in neural circuit development. Previous research has implicated the importance of NMDARs in pruning, but it remained unclear whether they played a direct or indirect role.
Zhang and colleagues focused on the thalamus, a brain region where synapse pruning and strengthening can be monitored and quantified with relative ease. They got unexpected help when they realized the mouse model they were using had thalamus cells lacking NMDARs right next to cells with normal NMDAR levels.
The researchers showed that the refinement process was disrupted in the absence of NMDARs. At the same time, neighboring neurons with the receptors proceeded through normal synaptic strengthening and pruning, clearly establishing the necessity of NMDARs in postsynaptic neurons for synaptic refinement.
"Whenever I give a talk or meet colleagues," Zhang says, "the first question that comes up is whether the NMDA receptor is important. It's good that this is now settled definitively."
There has been extensive research into synaptic strengthening, and most of these studies indicate that the presence of NMDARs may support the recruitment of larger numbers of another kind of glutamate receptor to strengthen the synaptic connections. How NMDARs regulate the pruning process remains largely unknown, however.
The Jackson Laboratory is an independent, nonprofit biomedical research institution based in Bar Harbor, Maine, with a facility in Sacramento, Calif., and a new genomic medicine institute in Farmington, Conn. It employs a total staff of more than 1,400. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

Story Source:

The above story is reprinted from materials provided by Jackson Laboratory.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:
Zhong-Wei Zhang, Matthew Peterson, Hong Liu. Essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses. Proceedings of the National Academy of Sciences, 2012; DOI: 10.1073/pnas.1212971110



Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/tSbHWJ

ScienceDaily: Latest Science News: Space travel may be harmful to the brain, study suggests; Prolonged cosmic radiation exposure could hasten Alzheimer's

ScienceDaily: Latest Science News

Breaking science news and articles on global warming, extrasolar planets, stem cells, bird flu, autism, nanotechnology, dinosaurs, evolution -- the latest discoveries in astronomy, anthropology, biology, chemistry, climate and environment, computers, engineering, health and medicine, math, physics, psychology, technology, and more -- from the world's leading universities and research organizations.

Space travel may be harmful to the brain, study suggests; Prolonged cosmic radiation exposure could hasten Alzheimer's
http://feeds.sciencedaily.com/~r/sciencedaily/~3/KBZnKWpQ1Gk/121231180632.htm
Dec 31st 2012, 23:06

Dec. 31, 2012 — As if space travel was not already filled with enough dangers, a new study out today in the journal PLOS ONE shows that cosmic radiation -- which would bombard astronauts on deep space missions to places like Mars -- could accelerate the onset of Alzheimer's disease.

"Galactic cosmic radiation poses a significant threat to future astronauts," said M. Kerry O'Banion, M.D., Ph.D., a professor in the University of Rochester Medical Center (URMC) Department of Neurobiology and Anatomy and the senior author of the study. "The possibility that radiation exposure in space may give rise to health problems such as cancer has long been recognized. However, this study shows for the first time that exposure to radiation levels equivalent to a mission to Mars could produce cognitive problems and speed up changes in the brain that are associated with Alzheimer's disease."
While space is full of radiation, the earth's magnetic field generally protects the planet and people in low earth orbit from these particles. However, once astronauts leave orbit, they are exposed to constant shower of various radioactive particles. With appropriate warning, astronauts can be shielded from dangerous radiation associated with solar flares. But there are also other forms of cosmic radiation that, for all intents and purposes, cannot be effectively blocked.
Because this radiation exists in low levels, the longer an astronaut is in deep space, the greater the exposure. This is a concern for NASA as the agency is planning manned missions to a distant asteroid in 2021 and to Mars in 2035. The round trip to the red planet, in particular, could take as long as three years.
For over 25 years, NASA has been funding research to determine the potential health risks of space travel in an effort to both develop countermeasures and determine whether or not the risks warranted sending men and women on extended missions in deep space.
Since that time, several studies have demonstrated the potential cancer, cardiovascular, and musculoskeletal impact of galactic cosmic radiation. The study out today for the first time examines the potential impact of space radiation on neurodegeneration, in particular, the biological processes in the brain that contribute to the development of Alzheimer's disease. O'Banion -- whose research focuses on how radiation affects the central nervous system -- and his team have been working with NASA for over eight years.
The researchers studied the impact of a particular form of radiation called high-mass, high-charged (HZE) particles. These particles -- which are propelled through space at very high speeds by the force of exploding stars -- come in many different forms. For this study the researcher chose iron particles. Unlikely hydrogen protons, which are produced by solar flares, the mass of HZE particles like iron, combined with their speed, enable them to penetrate solid objects such as the wall and protective shielding of a spacecraft.
"Because iron particles pack a bigger wallop it is extremely difficult from an engineering perspective to effectively shield against them," said O'Banion. "One would have to essentially wrap a spacecraft in a six-foot block of lead or concrete."
A portion of the research was conducted at the NASA Space Radiation Laboratory at Brookhaven National Laboratory on Long Island. NASA located its research operation at Brookhaven to take advantage of the Lab's particle accelerators which -- by colliding matter together at very high speeds -- can reproduce the radioactive particles found in space.
The researchers specifically wanted to examine whether or not radiation exposure had the potential to accelerate the biological and cognitive indicators of Alzheimer's disease, particularly in individuals who may be predisposed to developing the disease. To accomplish this they chose study the impact on animal models of Alzheimer's disease. These particular models have been extensively studied and scientists understand the precise timeframe in which the disease progresses over time.
At Brookhaven, the animals were exposed to various doses of radiation, including levels comparable to what astronauts would be experience during a mission to Mars. Back in Rochester, a team of researchers -- including URMC graduate student Jonathan Cherry, who was first author on the paper -- evaluated the cognitive and biological impact of the exposure. The mice underwent a series of experiments during which they had to recall objects or specific locations. The researchers observed that mice exposed to radiation were far more likely to fail these tasks -- suggesting neurological impairment -- earlier than these symptoms would typically appear.
The brains of the mice also showed signs of vascular alterations and a greater than normal accumulation of beta amyloid, the protein "plaque" that accumulates in the brain and is one of the hallmarks of the disease.
"These findings clearly suggest that exposure to radiation in space has the potential to accelerate the development of Alzheimer's disease," said O'Banion. "This is yet another factor that NASA, which is clearly concerned about the health risks to its astronauts, will need to take into account as it plans future missions."
Additional co-authors include Jacqueline Williams, Ph.D. and John Olschowka, Ph.D. with URMC and Bin Liu, Ph.D., Jeffrey Frost, and Cynthia Lemere, Ph.D. with Harvard Medical School. The study was funded by NASA.
Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

Story Source:

The above story is reprinted from materials provided by University of Rochester Medical Center.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:
Jonathan D. Cherry, Bin Liu, Jeffrey L. Frost, Cynthia A. Lemere, Jacqueline P. Williams, John A. Olschowka, M. Kerry O'Banion. Galactic Cosmic Radiation Leads to Cognitive Impairment and Increased Aβ Plaque Accumulation in a Mouse Model of Alzheimer's Disease. PLoS ONE, 2012; 7 (12): e53275 DOI: 10.1371/journal.pone.0053275



Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/tSbHWJ

ScienceDaily: Latest Science News: Jellyfish experts show increased blooms are a consequence of periodic global fluctuations

ScienceDaily: Latest Science News

Breaking science news and articles on global warming, extrasolar planets, stem cells, bird flu, autism, nanotechnology, dinosaurs, evolution -- the latest discoveries in astronomy, anthropology, biology, chemistry, climate and environment, computers, engineering, health and medicine, math, physics, psychology, technology, and more -- from the world's leading universities and research organizations.

Jellyfish experts show increased blooms are a consequence of periodic global fluctuations
http://feeds.sciencedaily.com/~r/sciencedaily/~3/YmN_P5tPyko/121231180617.htm
Dec 31st 2012, 23:06

Dec. 31, 2012 — Blooms, or proliferations, of jellyfish can show a substantial, visible impact on coastal populations -- clogged nets for fishermen, stinging waters for tourists, even choked cooling intake pipes for power plants -- and recent media reports have created a perception that the world's oceans are experiencing trending increases in jellyfish. Now, a new multinational collaborative study, involving the University of Southampton, suggests these trends may be overstated, finding that there is no robust evidence for a global increase in jellyfish over the past two centuries.

The results of the study, which includes lead co-author Dr Cathy Lucas, a marine biologist at the University of Southampton, appear in the latest issue of Proceedings of the National Academy of Sciences.
The key finding of the study shows global jellyfish populations undergo concurrent fluctuations with successive decadal periods of rise and fall, including a rising phase in the 1990s and early 2000s that has contributed to the current perception of a global increase in jellyfish abundance. The previous period of high jellyfish numbers during the 1970s went unnoticed due to limited research on jellyfish at the time, less awareness of global-scale problems and a lower capacity for information sharing (e.g. no Internet).
While there has been no increase over the long-term, the authors detected a hint of a slight increase in jellyfish since 1970, although this trend was countered by the observation that there was no difference in the proportion of increasing vs. decreasing jellyfish populations over time.
Dr Cathy Lucas, who is based at the National Oceanography Centre, Southampton, says: "Sustained monitoring is now required over the next decade to shed light with statistical confidence whether the weak increasing linear trend in jellyfish populations after 1970 is an actual shift in the baseline or part of a larger oscillation."
To date, media and scientific opinion for the current perception of a global increase in jellyfish was evidenced by a few local and regional case studies. Although there are areas where jellyfish have increased; the situation with the Giant Jellyfish in Japan and parts of the Mediterranean are classic examples, there are also areas where jellyfish numbers have remained stable, fluctuated over decadal periods, or actually decreased over time.
Increased speculation and discrepancies about current and future jellyfish blooms by the media and in climate and science reports formed the motivation for the study. "There are major consequences for getting the answer correct for tourism, fisheries and management decisions as they relate to climate change and changing ocean environments," says Dr Lucas. "The important aspect about our work is that we have provided the long-term baseline backed with all data available to science, which will enable scientists to build on and eventually repeat these analyses in a decade or two from now to determine whether there has been a real increase in jellyfish."
"The realisation that jellyfish synchronously rise and fall around the world should now lead researchers to search for the long-term natural and climate drivers of jellyfish populations, in addition to begin monitoring jellyfish in open ocean and Southern Hemisphere regions that are underrepresented in our analyses," says lead author Dr Rob Condon, marine scientist at the Dauphin Island Sea Lab (DISL) in Alabama.
Given the potential damage posed by jellyfish blooms to fisheries, tourism and other human industries, the findings of the group foretell recurrent phases of rise and fall in jellyfish populations that society should be prepared to face.
Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

Story Source:

The above story is reprinted from materials provided by University of Southampton, via AlphaGalileo.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:
Robert H. Condon, Carlos M. Duarte, Kylie A. Pitt, Kelly L. Robinson, Cathy H. Lucas, Kelly R. Sutherland, Hermes W. Mianzan, Molly Bogeberg, Jennifer E. Purcell, Mary Beth Decker, Shin-ichi Uye, Laurence P. Madin, Richard D. Brodeur, Steven H. D. Haddock, Alenka Malej, Gregory D. Parry, Elena Eriksen, Javier Quiñones, Marcelo Acha, Michel Harvey, James M. Arthur, and William M. Graham. Recurrent jellyfish blooms are a consequence of global oscillations. Proceedings of the National Academy of Sciences, 2012; DOI: 10.1073/pnas.1210920110



Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/tSbHWJ

焦点新闻-新浪科技: 中国概念股周一普遍上涨 奇虎涨9%

焦点新闻-新浪科技

科技焦点新闻

中国概念股周一普遍上涨 奇虎涨9%
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06137940620.shtml
Dec 31st 2012, 22:13

中国概念股周一行情

  新浪科技讯 1月1日早晨消息,2012年最后一个交易日,周一美国股市大幅收高,中国概念股多数上涨,其中。麦考林、奇虎360、世纪互联等涨幅超过8%。
  美东时间12月31日16:00(北京时间1月1日05:00),道琼斯工业平均指数上涨166.03点,收于13,104.14点,涨幅为1.28%;纳斯达克综合指数上涨59.20点,收于3,019.51点,涨幅为2.00%;标准普尔500指数上涨23.77点,收于1,426.20点,涨幅为1.69%。
  中国概念股方面,新浪报50.22美元,涨幅3.86%;网易报42.53美元,涨幅0.45%;搜狐报47.34美元,涨幅1.87%;奇虎360报29.69美元,涨幅8.64%。(爱文)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

焦点新闻-新浪科技: 人人的下一步:社交面临天花板 移动处窗口期

焦点新闻-新浪科技

科技焦点新闻

人人的下一步:社交面临天花板 移动处窗口期
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06417940625.shtml
Dec 31st 2012, 22:41

  在SNS 领域进步缓慢的人人,却在游戏和移动应用领域高歌猛进。人人面临着抉择。
  虽然在2012年前3季度财报皆为亏损,但陈一舟似乎并未因此而烦恼。
  事实上,2011年以来,除了2011年第4季度靠出售艺龙股权盈利以外,人人的每一个季度都处于亏损状态。
  陈一舟的淡定的确有事实支撑:自2012年第1季度开始,游戏业务在人人网收入中的比例已经超过了50%。而在11月份发布的第3季度财报显示,人人在线游戏收入为2420万美元,较2011年第3季度已经增长120.2%。
  关键是,此时已经有一半的用户通过移动终端登录人人网。而除了网页游戏之外,人人网的移动游戏也在世界各大应用商店中名列前茅。
  很长时间内,很多人都认为,人人网在美国的名声,与在国内互联网业内的地位并不匹配,其CEO陈一舟则更像是一位善于融资的CFO。
  然而,在移动互联网大潮不断淘洗传统互联网格局之时,及早布局的陈一舟和他的人人网却有可能实现蜕变。
  面对移动互联网大潮带来的这种机遇与危机并存,能否趋利避害,还取决于陈一舟的战略眼光。
  社交的天花板
  2011年5月初,人人网凭借"中国Facebook"的概念上市,这一时间比Facebook的上市时间还要早半个月。
  与Facebook跌破发行价不同,人人网上市后的股价大幅上涨,融资额超过7.4亿美元,成为中国迄今赴美上市的企业中融资额最高的企业。之所以取得如此可观的成就,是因为陈一舟将人人的概念打造成了"Facebook+Zynga+Groupon+Linkedin"(即人人网+游戏+糯米网+经纬网),四者是近年美国最为热门的互联网公司。
  事实证明,四位一体中恐怕只有与"Zynga"对应的业务部分可以爆发出巨大价值。
  人人脱胎于王兴创办的校内网,至今仍是在校学生的SNS,用户步入社会后即转投他处是人人网一直没有解决的要害问题。因为用户的局限性,使得人人网难以成功复制Facebook的平台效应。
  截至2011年末,全球已有超过250万家网站,通过Facebook Connect或是"like"按键被整合进了Facebook平台,每天平均有1万家网站都在加入这一阵营,该模式未来有可能延伸出谷歌的类似于AdSense模式,把Facebook平台以外的流量聚拢起来,产生广告价值——这些显然是人人所不具备的能力。
  既然入口价值体现不出来,那么人人四位一体中的与"Facebook"和" LinkedIn"对应的成分所能产生的价值就十分有限。在盈利数额为1737.9万美元的2010年,人人网的用户年ARPU值仅为0.15美元,远远低于腾讯和Facebook。
  而更为重要的是,在移动互联网大潮来袭之时,无论是Facebook还是人人网都面临着严峻的挑战。
  移动大潮意味着用户体验与广告展现方式的双重颠覆。在超过一半以上用户已经由移动终端登录的时刻,来自移动端的广告增长在近期内还无法弥补PC端的广告损失。正是这种流量转移之痛,使得诞生以来都顺风顺水的Facebook在2012年撞上了"冰山",拱手将美国展示广告的市场老大地位再次还给谷歌。
  而财报表明,今年第3季度人人网的在线广告业务收入为1700万美元,较2011年第3季度下降13.7%(因为行业波动,较2012年第2季度增长12.6%),形势已经十分严峻。
  至于糯米网,的确它在打造人人网绚丽业务概念上市时功不可没,但实践证明它一直以来都是人人的负资产,并且比重颇大。
  整个2011年度,除去糯米网,人人的净利润为6560万美元,即使不计入从出售艺龙股票中获得了5090万美元一次性收益,人人依旧实现了1470万美元的净利润。但糯米网一项的亏损就达到了2430美元,使得人人的财报总体亏损。
  在刚刚过去的2012年第3季度,人人调整后净亏损1210万美元中,来自糯米网的亏损就有620万美元,占总亏损的51%。
  在上市之后,陈一舟又收购了56视频,并且其旗下还有汽车网站和婚恋网站。
  从理论上说,这些资产都可以通过人人网的SNS属性导入浏览量,但正如前面的分析,在行业局面紧迫的时刻,陈一舟到了对产品线进行重新规划的时候了。
  移动的窗口期
  陈一舟是名副其实的互联网老兵,经历了完整的中国互联网的潮流变迁,并且以热衷追随新的互联网产品而闻名。人人就几乎尝试过2005年之后的几乎所有互联网产品形态。
  对此,业内人士持不以为然态度的居多,其中也不乏刻薄之词。
  就在11月中旬YY登录纳斯达克之时,科技博客PingWest的创始人骆轶航还把人人与YY做了一番对比。
  "在YY上市的时候,它注册用户已超过4亿,月活跃人数7500万,同时在线用户超过1000万,而公司已盈利;在人人上市的时候,它的注册用户1亿,月活跃用户1000万左右,之前一个季度仍在亏损。但人人上市后的市值是YY的10多倍,YY上市之后仍是一家不足10亿美元的公司。" 骆轶航写道:"这就是不一样的故事带来的不一样的结果。"
  事实上,在2006年SP业务关上大门之后,人人开始深耕网页游戏,这也正是陈一舟"跟随"潮流的举措。实践证明,那次的跟随是明智之举,搭上了从PC客户端游戏向网页游戏的转型潮流。
  陈一舟对移动互联网的"跟随",可以追溯到2010年初。显然,这一次陈一舟再一次判断对了方向,并且收获颇丰。
  登录App Store,人们发现至少50款以游戏为主的人人出品的应用,这种量的优势在中国的应用开发势力里面首屈一指。
  根据App Annie的监测,人人网在App Store中的收入长期排在北美区App Store收入的前100名。
  尼毕鲁的创始人杨祥吉是2012年引人注目的中国开发者,在年初其出品的《银河帝国》成为北美区App Store畅销榜第1名。一开春,一直在成都创业的杨祥吉跑到北京拜访各路游戏开发者。回到成都后,他发了一条微博:"这次在北京收获很多,游戏这一行藏龙卧虎……北京有一家规模达700多人的游戏开发团队,跟他们的收入比起来,尼毕鲁取得的这点成绩真不算什么。"杨祥吉说的就是人人的游戏团队。
  自2011年提出"多屏娱乐"的概念以来,人人网的游戏研发队伍迅速膨胀,由何川带领的位于酒仙桥的游戏研发团队已经接近800人。其出品的每一款游戏几乎都有iOS和Android版本,为用户提供跨平台体验。
  人人网早在2009年便开始打造游戏平台,并在去年末宣布了移动端的零分成政策吸引开发者。
  目前人人网平台上有大约15款自己研发的游戏,50款第三方开发的游戏。在目前已经占到总收入半数以上的游戏业务中,排名前5的游戏贡献了73%。
  据易观国际分析师李智的跟踪研究,这5款游戏分别为《乱世天下》,《决战三国》,《怒海争锋》,《名将传奇》与《天书奇谈》。其中除《决战三国》外均为人人网研发。而MMORPG游戏《天书奇谈》已经是持续"火"了4年的网游产品,这说明人人的网游研发实力确实不容小觑。
  陈一舟曾经对外表示,"坚持"与"灵活"是他的创业方法论。然而外界更多感知的是他的"灵活"。其实,如果说陈一舟真的践行过"坚持"的方向,不顾损益表而大力投入移动互联网的行为肯定算一个。
  糯米网固然是人人继续亏损的一个原因,但同时陈一舟对移动研发方面的投入却是另一个重要原因。人人的产品部门划分比较复杂,分为人人网产品部门,由黄晶负责;有移动产品部门,由吴疆负责;还有游戏部门,由何川负责。3个部门相互独立又相互关联,但相同之处在于三者都在招兵买马。
  人人的2012年第1季财报显示,其运营成本竟然增加了150%。陈一舟在分析师会议中表示,这些增加的成本大部分来源于与移动产品相关研发人员的增加,比如今年刚刚增加的移动广告部门,而这一部门短期内还谈不上盈利。
  虽然从功利角度来看陈一舟不可谓不成功,但在很多人眼中,他更像是一个跑动积极并善于捕捉临门一脚机会的前锋,而不是对大局运筹帷幄的出色教练。当然,实现前者已属不易,这要求准确的判断力和强大的执行力。
  然而,在风险与机遇并存的大潮来袭时,哪些该"坚持",哪些该"灵活",这是陈一舟面临的大考。
  由于入场较早,人人已经把握住了移动互联的窗口期并成功卡位,但前面的路还很长。从现有的条件看,除了割除冗余的产品线之外,人人转型为移动社交巨头,或者打造独立的网游帝国并不是没有可能。但前提是陈一舟在"舍"与"得"之间拿捏得当。
  特别是相对于其他游戏平台,人人游戏的ARPU还比较低,原因仍是其平台上的用户多为学生。在社交圈子短时间内难以跨界的情况下,游戏的运营触角一定要伸的尽量长。另外,除了靠游戏赚快钱之外,陈一舟很有必要认真考察现在以移动应用为载体的创新社交模式——无论是美国的Path、Instagram Reddit、Tumbl还是中国的唱吧和啪啪,都是人人网化整为零进行用户群"突围"的可行路径。
  可以肯定的是,如果想成为一家受到尊敬的互联网公司,人人需要抛弃对拼凑热门模式的热衷,而改为对长线的产品规划和系统的平台架构的专注,以及对外展示出一种更为开放的形象。
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

互联网新闻-新浪科技: 交易提示:1日美股全天休市

互联网新闻-新浪科技

互联网新闻

交易提示:1日美股全天休市
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06047940619.shtml
Dec 31st 2012, 22:04

  新浪科技讯 1月1日上午消息,美国股市1月1日因元旦全天休市,1月2日正常交易。
  2013年美股有9个交易日全天休市,分别是:1月1日元旦、1月21日马丁-路德金纪念日、2月18日华盛顿纪念日、3月29日耶稣受难日、5月27日阵亡将士纪念日、7月4日独立日、9月2日劳工节、11月28日感恩节和12月25日圣诞节。(爱文)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

互联网新闻-新浪科技: 中国概念股周一普遍上涨 奇虎涨9%

互联网新闻-新浪科技

互联网新闻

中国概念股周一普遍上涨 奇虎涨9%
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06137940620.shtml
Dec 31st 2012, 22:13

中国概念股周一行情

  新浪科技讯 1月1日早晨消息,2012年最后一个交易日,周一美国股市大幅收高,中国概念股多数上涨,其中。麦考林、奇虎360、世纪互联等涨幅超过8%。
  美东时间12月31日16:00(北京时间1月1日05:00),道琼斯工业平均指数上涨166.03点,收于13,104.14点,涨幅为1.28%;纳斯达克综合指数上涨59.20点,收于3,019.51点,涨幅为2.00%;标准普尔500指数上涨23.77点,收于1,426.20点,涨幅为1.69%。
  中国概念股方面,新浪报50.22美元,涨幅3.86%;网易报42.53美元,涨幅0.45%;搜狐报47.34美元,涨幅1.87%;奇虎360报29.69美元,涨幅8.64%。(爱文)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

互联网新闻-新浪科技: 人人的下一步:社交面临天花板 移动处窗口期

互联网新闻-新浪科技

互联网新闻

人人的下一步:社交面临天花板 移动处窗口期
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06417940625.shtml
Dec 31st 2012, 22:41

  在SNS 领域进步缓慢的人人,却在游戏和移动应用领域高歌猛进。人人面临着抉择。
  虽然在2012年前3季度财报皆为亏损,但陈一舟似乎并未因此而烦恼。
  事实上,2011年以来,除了2011年第4季度靠出售艺龙股权盈利以外,人人的每一个季度都处于亏损状态。
  陈一舟的淡定的确有事实支撑:自2012年第1季度开始,游戏业务在人人网收入中的比例已经超过了50%。而在11月份发布的第3季度财报显示,人人在线游戏收入为2420万美元,较2011年第3季度已经增长120.2%。
  关键是,此时已经有一半的用户通过移动终端登录人人网。而除了网页游戏之外,人人网的移动游戏也在世界各大应用商店中名列前茅。
  很长时间内,很多人都认为,人人网在美国的名声,与在国内互联网业内的地位并不匹配,其CEO陈一舟则更像是一位善于融资的CFO。
  然而,在移动互联网大潮不断淘洗传统互联网格局之时,及早布局的陈一舟和他的人人网却有可能实现蜕变。
  面对移动互联网大潮带来的这种机遇与危机并存,能否趋利避害,还取决于陈一舟的战略眼光。
  社交的天花板
  2011年5月初,人人网凭借"中国Facebook"的概念上市,这一时间比Facebook的上市时间还要早半个月。
  与Facebook跌破发行价不同,人人网上市后的股价大幅上涨,融资额超过7.4亿美元,成为中国迄今赴美上市的企业中融资额最高的企业。之所以取得如此可观的成就,是因为陈一舟将人人的概念打造成了"Facebook+Zynga+Groupon+Linkedin"(即人人网+游戏+糯米网+经纬网),四者是近年美国最为热门的互联网公司。
  事实证明,四位一体中恐怕只有与"Zynga"对应的业务部分可以爆发出巨大价值。
  人人脱胎于王兴创办的校内网,至今仍是在校学生的SNS,用户步入社会后即转投他处是人人网一直没有解决的要害问题。因为用户的局限性,使得人人网难以成功复制Facebook的平台效应。
  截至2011年末,全球已有超过250万家网站,通过Facebook Connect或是"like"按键被整合进了Facebook平台,每天平均有1万家网站都在加入这一阵营,该模式未来有可能延伸出谷歌的类似于AdSense模式,把Facebook平台以外的流量聚拢起来,产生广告价值——这些显然是人人所不具备的能力。
  既然入口价值体现不出来,那么人人四位一体中的与"Facebook"和" LinkedIn"对应的成分所能产生的价值就十分有限。在盈利数额为1737.9万美元的2010年,人人网的用户年ARPU值仅为0.15美元,远远低于腾讯和Facebook。
  而更为重要的是,在移动互联网大潮来袭之时,无论是Facebook还是人人网都面临着严峻的挑战。
  移动大潮意味着用户体验与广告展现方式的双重颠覆。在超过一半以上用户已经由移动终端登录的时刻,来自移动端的广告增长在近期内还无法弥补PC端的广告损失。正是这种流量转移之痛,使得诞生以来都顺风顺水的Facebook在2012年撞上了"冰山",拱手将美国展示广告的市场老大地位再次还给谷歌。
  而财报表明,今年第3季度人人网的在线广告业务收入为1700万美元,较2011年第3季度下降13.7%(因为行业波动,较2012年第2季度增长12.6%),形势已经十分严峻。
  至于糯米网,的确它在打造人人网绚丽业务概念上市时功不可没,但实践证明它一直以来都是人人的负资产,并且比重颇大。
  整个2011年度,除去糯米网,人人的净利润为6560万美元,即使不计入从出售艺龙股票中获得了5090万美元一次性收益,人人依旧实现了1470万美元的净利润。但糯米网一项的亏损就达到了2430美元,使得人人的财报总体亏损。
  在刚刚过去的2012年第3季度,人人调整后净亏损1210万美元中,来自糯米网的亏损就有620万美元,占总亏损的51%。
  在上市之后,陈一舟又收购了56视频,并且其旗下还有汽车网站和婚恋网站。
  从理论上说,这些资产都可以通过人人网的SNS属性导入浏览量,但正如前面的分析,在行业局面紧迫的时刻,陈一舟到了对产品线进行重新规划的时候了。
  移动的窗口期
  陈一舟是名副其实的互联网老兵,经历了完整的中国互联网的潮流变迁,并且以热衷追随新的互联网产品而闻名。人人就几乎尝试过2005年之后的几乎所有互联网产品形态。
  对此,业内人士持不以为然态度的居多,其中也不乏刻薄之词。
  就在11月中旬YY登录纳斯达克之时,科技博客PingWest的创始人骆轶航还把人人与YY做了一番对比。
  "在YY上市的时候,它注册用户已超过4亿,月活跃人数7500万,同时在线用户超过1000万,而公司已盈利;在人人上市的时候,它的注册用户1亿,月活跃用户1000万左右,之前一个季度仍在亏损。但人人上市后的市值是YY的10多倍,YY上市之后仍是一家不足10亿美元的公司。" 骆轶航写道:"这就是不一样的故事带来的不一样的结果。"
  事实上,在2006年SP业务关上大门之后,人人开始深耕网页游戏,这也正是陈一舟"跟随"潮流的举措。实践证明,那次的跟随是明智之举,搭上了从PC客户端游戏向网页游戏的转型潮流。
  陈一舟对移动互联网的"跟随",可以追溯到2010年初。显然,这一次陈一舟再一次判断对了方向,并且收获颇丰。
  登录App Store,人们发现至少50款以游戏为主的人人出品的应用,这种量的优势在中国的应用开发势力里面首屈一指。
  根据App Annie的监测,人人网在App Store中的收入长期排在北美区App Store收入的前100名。
  尼毕鲁的创始人杨祥吉是2012年引人注目的中国开发者,在年初其出品的《银河帝国》成为北美区App Store畅销榜第1名。一开春,一直在成都创业的杨祥吉跑到北京拜访各路游戏开发者。回到成都后,他发了一条微博:"这次在北京收获很多,游戏这一行藏龙卧虎……北京有一家规模达700多人的游戏开发团队,跟他们的收入比起来,尼毕鲁取得的这点成绩真不算什么。"杨祥吉说的就是人人的游戏团队。
  自2011年提出"多屏娱乐"的概念以来,人人网的游戏研发队伍迅速膨胀,由何川带领的位于酒仙桥的游戏研发团队已经接近800人。其出品的每一款游戏几乎都有iOS和Android版本,为用户提供跨平台体验。
  人人网早在2009年便开始打造游戏平台,并在去年末宣布了移动端的零分成政策吸引开发者。
  目前人人网平台上有大约15款自己研发的游戏,50款第三方开发的游戏。在目前已经占到总收入半数以上的游戏业务中,排名前5的游戏贡献了73%。
  据易观国际分析师李智的跟踪研究,这5款游戏分别为《乱世天下》,《决战三国》,《怒海争锋》,《名将传奇》与《天书奇谈》。其中除《决战三国》外均为人人网研发。而MMORPG游戏《天书奇谈》已经是持续"火"了4年的网游产品,这说明人人的网游研发实力确实不容小觑。
  陈一舟曾经对外表示,"坚持"与"灵活"是他的创业方法论。然而外界更多感知的是他的"灵活"。其实,如果说陈一舟真的践行过"坚持"的方向,不顾损益表而大力投入移动互联网的行为肯定算一个。
  糯米网固然是人人继续亏损的一个原因,但同时陈一舟对移动研发方面的投入却是另一个重要原因。人人的产品部门划分比较复杂,分为人人网产品部门,由黄晶负责;有移动产品部门,由吴疆负责;还有游戏部门,由何川负责。3个部门相互独立又相互关联,但相同之处在于三者都在招兵买马。
  人人的2012年第1季财报显示,其运营成本竟然增加了150%。陈一舟在分析师会议中表示,这些增加的成本大部分来源于与移动产品相关研发人员的增加,比如今年刚刚增加的移动广告部门,而这一部门短期内还谈不上盈利。
  虽然从功利角度来看陈一舟不可谓不成功,但在很多人眼中,他更像是一个跑动积极并善于捕捉临门一脚机会的前锋,而不是对大局运筹帷幄的出色教练。当然,实现前者已属不易,这要求准确的判断力和强大的执行力。
  然而,在风险与机遇并存的大潮来袭时,哪些该"坚持",哪些该"灵活",这是陈一舟面临的大考。
  由于入场较早,人人已经把握住了移动互联的窗口期并成功卡位,但前面的路还很长。从现有的条件看,除了割除冗余的产品线之外,人人转型为移动社交巨头,或者打造独立的网游帝国并不是没有可能。但前提是陈一舟在"舍"与"得"之间拿捏得当。
  特别是相对于其他游戏平台,人人游戏的ARPU还比较低,原因仍是其平台上的用户多为学生。在社交圈子短时间内难以跨界的情况下,游戏的运营触角一定要伸的尽量长。另外,除了靠游戏赚快钱之外,陈一舟很有必要认真考察现在以移动应用为载体的创新社交模式——无论是美国的Path、Instagram Reddit、Tumbl还是中国的唱吧和啪啪,都是人人网化整为零进行用户群"突围"的可行路径。
  可以肯定的是,如果想成为一家受到尊敬的互联网公司,人人需要抛弃对拼凑热门模式的热衷,而改为对长线的产品规划和系统的平台架构的专注,以及对外展示出一种更为开放的形象。
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

科技要闻-新浪科技: 交易提示:1日美股全天休市

科技要闻-新浪科技

科技时代-科技要闻

交易提示:1日美股全天休市
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06047940619.shtml
Dec 31st 2012, 22:04

  新浪科技讯 1月1日上午消息,美国股市1月1日因元旦全天休市,1月2日正常交易。
  2013年美股有9个交易日全天休市,分别是:1月1日元旦、1月21日马丁-路德金纪念日、2月18日华盛顿纪念日、3月29日耶稣受难日、5月27日阵亡将士纪念日、7月4日独立日、9月2日劳工节、11月28日感恩节和12月25日圣诞节。(爱文)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/Cjnnlk

科技要闻-新浪科技: 中国概念股周一普遍上涨 奇虎涨9%

科技要闻-新浪科技

科技时代-科技要闻

中国概念股周一普遍上涨 奇虎涨9%
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06137940620.shtml
Dec 31st 2012, 22:13

中国概念股周一行情

  新浪科技讯 1月1日早晨消息,2012年最后一个交易日,周一美国股市大幅收高,中国概念股多数上涨,其中。麦考林、奇虎360、世纪互联等涨幅超过8%。
  美东时间12月31日16:00(北京时间1月1日05:00),道琼斯工业平均指数上涨166.03点,收于13,104.14点,涨幅为1.28%;纳斯达克综合指数上涨59.20点,收于3,019.51点,涨幅为2.00%;标准普尔500指数上涨23.77点,收于1,426.20点,涨幅为1.69%。
  中国概念股方面,新浪报50.22美元,涨幅3.86%;网易报42.53美元,涨幅0.45%;搜狐报47.34美元,涨幅1.87%;奇虎360报29.69美元,涨幅8.64%。(爱文)
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/Cjnnlk

焦点新闻-新浪科技: 交易提示:1日美股全天休市

焦点新闻-新浪科技

科技焦点新闻

交易提示:1日美股全天休市
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2013-01-01/06047940619.shtml
Dec 31st 2012, 22:04

[unable to retrieve full-text content]  新浪科技讯 1月1日上午消息,美国股市1月1日因元旦全天休市,1月2日正常交易。

  2013年美股有9个交易日全天休市,分别是:1月1日元旦、1月21日马丁-路德金纪念日、2月18日华盛顿纪念日、3月29日耶稣受难日、5月27日阵亡将士纪念日、7月4日独立日、9月2日劳工节、11月28....



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/5pkTB5

互联网新闻-新浪科技: 知名盗版应用社区Hackulous宣布关闭

互联网新闻-新浪科技

互联网新闻

知名盗版应用社区Hackulous宣布关闭
http://go.rss.sina.com.cn/redirect.php?url=http://tech.sina.com.cn/i/2012-12-31/23387940407.shtml
Dec 31st 2012, 15:38

[unable to retrieve full-text content]  新浪科技讯 北京时间12月31日晚间消息,作为互联网上最知名的破解应用社区之一,Hackulous上周日突然关闭。与此同时,最受欢迎的iOS破解应用下载中心AppTrackr也被关闭,下载工具Installous也被禁用。

  Hackulous表示,主要是因为用户活跃度不高而导致社区冷清,因此才....



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/FKWDlq

ScienceDaily: Latest Science News: Hydrogen peroxide vapor enhances hospital disinfection of superbugs

ScienceDaily: Latest Science News

Breaking science news and articles on global warming, extrasolar planets, stem cells, bird flu, autism, nanotechnology, dinosaurs, evolution -- the latest discoveries in astronomy, anthropology, biology, chemistry, climate and environment, computers, engineering, health and medicine, math, physics, psychology, technology, and more -- from the world's leading universities and research organizations.

Hydrogen peroxide vapor enhances hospital disinfection of superbugs
http://feeds.sciencedaily.com/~r/sciencedaily/~3/bnXV_hVn6io/121231110514.htm
Dec 31st 2012, 16:05

Dec. 31, 2012 — Infection control experts at The Johns Hopkins Hospital have found that a combination of robot-like devices that disperse a bleaching agent into the air and then detoxify the disinfecting chemical are highly effective at killing and preventing the spread of multiple-drug-resistant bacteria, or so-called hospital superbugs.

A study report on the use of hydrogen peroxide vaporizers -- first deployed in several Singapore hospitals during the 2002 outbreak of severe acute respiratory syndrome, or SARS, and later stocked by several U.S. government agencies in case of an anthrax attack -- is to be published Jan. 1 in the journal Clinical Infectious Diseases.
In the study, the Johns Hopkins team placed the devices in single hospital rooms after routine cleaning to disperse a thin film of the bleaching hydrogen peroxide across all exposed hospital equipment surfaces, as well as on room floors and walls. Results showed that the enhanced cleaning reduced by 64 percent the number of patients who later became contaminated with any of the most common drug-resistant organisms. Moreover, researchers found that protection from infection was conferred on patients regardless of whether the previous room occupant was infected with drug-resistant bacteria or not.
"Hydrogen peroxide vapor, as spread around patients' rooms by these devices, represents a major technological advance in preventing the spread of dangerous bacteria inside hospitals and, especially, from one patient occupant to the next, even though sick patients were never in the same room at the same time," says infectious disease specialist and study senior investigator Trish Perl, M.D., M.Sc.
Of special note, researchers say, was that enhanced cleaning with the vapor reduced by 80 percent a patient's chances of becoming colonized by a particularly aggressive and hard-to-treat bacterium, vancomycin-resistant enterococci (VRE).
In what is believed to be the first head-to-head comparison between traditional hand-cleaning and mopping with bleaching agents and robotic vaporizers, researchers routinely tested patients and their surroundings not only for VRE, but also for the more common methicillin-resistant Staphylococcus aureus, or MRSA, and lesser-known bacteria, including Clostridium difficile and Acinetobacter baumannii.
Some 6,350 patient admissions to JHH were closely tracked as part of the two-and-a-half-year analysis, as patients moved into and out of 180 private hospital rooms. Almost half the rooms received enhanced cleaning with hydrogen peroxide vapor in between patients, while the rest did not. Overall, multiple-drug-resistant organisms were found on room surfaces in 21 percent of rooms tested, but mostly in rooms that did not undergo enhanced cleaning.
Perl says that patients bringing in or picking up drug-resistant organisms while undergoing treatment in hospitals is a persistent and growing problem, and previous research has shown that patients who stay in a hospital room previously occupied by an infected patient are at greater risk of becoming infected.
"Our study results are evidence that technological solutions, when combined with standard cleaning, can effectively and systematically decontaminate patients' rooms and augment other behavioral practices, such as strict hospital staff compliance with hand-washing and bathing patients in disinfecting chlorhexidine when they are first admitted to the hospital," says Perl, senior hospital epidemiologist for the Johns Hopkins Health System and a professor at the Johns Hopkins University School of Medicine.
"Our goal is to improve all hospital infection control practices, including cleaning and disinfection, as well as behavioral and environmental practices, to the point where preventing the spread of these multiple-drug-resistant organisms also minimizes the chances of patients becoming infected and improves their chances of recovery," says Perl.
The paired robot-like devices, each about the size of a washing machine and weighing nearly 60 pounds, as well as supplies used in the study, were provided by their manufacturer, Bioquell Inc. of Horsham, Pa.
After the room has been cleaned, the vents are covered and the two devices are placed inside. The sliding door is closed, and the room is sealed. Then, the larger of the two devices disperses hydrogen peroxide into the room, leaving a very tiny, almost invisible layer (only 2 microns to 6 microns in thickness) on all exposed surfaces, including keyboards and monitors, as well as tables and chairs.
Because hydrogen peroxide can be toxic to humans if ingested or corrosive if left on the skin for too long, the second, smaller device is activated to break down the bleach into its component water and oxygen parts. The combined operation takes the devices about an hour and a half to complete.
"What is so exciting about this new method of infection control is that the devices are easy to use and hospital staff embrace it very quickly," says surgeon and study co-investigator Pamela Lipsett, M.D., M.H.P.E. Lipsett, a professor and director of surgical and critical care fellowship training at Johns Hopkins, says that during the study and before room cleanings, staff were "wheeling in" other pieces of equipment so these, too, could be decontaminated by the hydrogen peroxide vapor.
As a result of the study and the researchers' recommendation, JHH has purchased two of the Bioquell decontaminating units, which cost more than $40,000 per pair. The devices, already in use at some 20 other hospitals across the country, will be used at Johns Hopkins to decontaminate rooms typically housing high-risk patients under strict isolation precautions because of severe infection with a multiple-drug-resistant organism.
Researchers say they next plan to study the devices' effectiveness at decontaminating the outside packaging of unused but potentially exposed hospital supplies, which are typically discarded even though their seals remain intact. The research team also wants to coordinate study testing among other hospitals to validate their Johns Hopkins findings. Larger and longer studies may also be planned, to precisely measure and determine how well the devices work against the spread of each hospital superbug. The current study had only sufficient numbers to statistically validate the paired unit's effectiveness against VRE.
In addition to Perl and Lipsett, other Johns Hopkins University investigators involved in this study were study lead investigator Catherine Passaretti, M.D.; Nicholas Reich, Ph.D.; Jessica Meyers, M.P.H.; John Shepard, M.B.A.; and Karen Carroll, M.D. Additional study assistance was provided by Jonathan Otter, at Bioquell Inc., and Tracy Ross, at the University of Massachusetts, in Amherst.
Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

Story Source:

The above story is reprinted from materials provided by Johns Hopkins Medicine, via Newswise.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:
C. L. Passaretti, J. A. Otter, N. G. Reich, J. Myers, J. Shepard, T. Ross, K. C. Carroll, P. Lipsett, T. M. Perl. An Evaluation of Environmental Decontamination With Hydrogen Peroxide Vapor for Reducing the Risk of Patient Acquisition of Multidrug-Resistant Organisms. Clinical Infectious Diseases, 2012; 56 (1): 27 DOI: 10.1093/cid/cis839



Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/tSbHWJ

ScienceDaily: Latest Science News: Paired CT scans catch chemo-killing of liver tumors in real time

ScienceDaily: Latest Science News

Breaking science news and articles on global warming, extrasolar planets, stem cells, bird flu, autism, nanotechnology, dinosaurs, evolution -- the latest discoveries in astronomy, anthropology, biology, chemistry, climate and environment, computers, engineering, health and medicine, math, physics, psychology, technology, and more -- from the world's leading universities and research organizations.

Paired CT scans catch chemo-killing of liver tumors in real time
http://feeds.sciencedaily.com/~r/sciencedaily/~3/BxsY8Gnb_98/121231110516.htm
Dec 31st 2012, 16:05

Dec. 31, 2012 — Using two successive pairs of specialized CT scans, a team of Johns Hopkins and Dutch radiologists has produced real-time images of liver tumors dying from direct injection of anticancer drugs into the tumors and their surrounding blood vessels. Within a minute, the images showed whether the targeted chemotherapy did or did not choke off the tumors' blood supply and saved patients a month of worry about whether the treatment, known as chemoembolization, was working or not, and whether repeat or more powerful treatments were needed.

The Johns Hopkins team's report about this novel use of dual-phase cone-bean computed tomography, or DPCBCT, an imaging technique developed at Johns Hopkins, is set to appear in the January 2013 edition of the journal Radiology. The diagnostic scans were performed on 27 men and women with inoperable liver cancer.
"This new scanning method is giving us almost instant feedback about the value of injecting antitumor drugs directly into large liver tumors and their surrounding blood vessels in an effort to quickly kill them, and to prevent the cancer from spreading," says senior study investigator and interventional radiologist Jean-Francois Geschwind, M.D.
Geschwind says if further testing proves equally successful, the paired use of cone-beam CT scans, which are already approved for single-scan use by the U.S. Food and Drug Administration, could supplant the current practice of MRI scanning a month after chemoembolization to check its effects.
"Patients should not have to endure the uncertainty of waiting weeks or more to find out if their chemoembolization was successful in fighting their liver cancer," says Geschwind, a professor in the Russell H. Morgan Department of Radiology at the Johns Hopkins University School of Medicine and its Kimmel Cancer Center.
"Dual-phase cone-beam CT avoids such delays, which also could allow the cancer to grow and spread and, ultimately, compromise chances of remission," he says.
Avoiding delays is particularly important, he says, for people with moderate to advanced stages of the disease, when liver tumors are too large or too numerous to surgically remove, and for whom chemoembolization is the main treatment option. Half of such liver cancer patients succumb within nine months, and liver transplantation is only an option for a quarter of those whose tumors have not spread outside the liver.
The newer DPCBCT scans, in which X-rays are detected by a device the size of a large laptop that can be placed directly below or above the operating room table, have the added advantage of being performed in the same room, or interventional radiology suite, as patients getting chemoembolization.
In their new study, Geschwind and his colleagues found that the initial shrinkage seen with DPCBCT scans taken before and after chemoembolization matched up almost perfectly with MRI scans taken a month later. Tumor death was 95 percent, the same as that seen by MRI. A total of 47 tumors were closely monitored in the study to assess how well DPCBCT tracked tumor death after chemoembolization.
All study participants were treated at The Johns Hopkins Hospital between March and December 2009.
In DPCBCT scanning, a chemical contrast dye is injected into the artery that supplies blood flow to the liver and tumor right before the chemotherapy drug is injected, to enhance the X-ray image. The first set of scans highlights key blood vessels feeding the tumor, as dye flows in and out of the tumor. The second set of scans is performed immediately after chemoembolization, to gauge tumor and key blood vessel death. Computer software is used to sharpen and analyze differences between the images.
The entire DPCBCT scanning time, researchers say, is between 20 seconds and 30 seconds, and the total amount of radiation exposure from the dual scanning averages 3.08 milliseiverts, which is less than half the amount of radiation involved in a modern abdominal 64-CT scan. Cone-beam CT scanners also emit an X-ray, but unlike other CT scanners, the cone-beam type of X-ray is projected onto one large, rectangular detector, roughly a foot and a half long -- and produces a telltale conical shape. The size of the cone-beam CT detector allows for single scans that can capture images the size of most people's entire liver. More powerful 64-CT and 320-CT scanners involve multiple detector rows.
Chemoembolization entails the use of tiny beads containing the chemotherapy drug doxorubicin injected directly into liver tumors.
Ultrathin catheters, about the width of a human hair, are threaded through blood vessels to deliver the drugs, which seep from the beads for several weeks.
Geschwind is leading clinical trials under way at Johns Hopkins and other centers to assess whether the combination drug treatment works for liver cancer patients. Early results have shown promise, with patients with advanced disease living 10 months to 15 months longer.
Geschwind says they plan improvements in image quality in DPCBCT scans, hoping further refinements will encourage physicians to adopt the technique. They also plan updates to the navigational software that, like GPS, can track blood vessels feeding each tumor, and provide more precise and greater numbers of targets.
Liver cancer kills nearly 20,000 Americans each year, and is much more prevalent outside the United States, where it is among the top three causes of cancer death in the world. Experts cite the rising numbers of hepatitis C infections, which cause chronic liver inflammation and are a leading risk factor for liver cancer.
Funding support for this study was provided by the French Society of Radiology and Philips Research North America in Briarcliff Manor, N.Y. Philips, whose parent company is based in the Netherlands, manufactures the CBCT device used in the study. Additional funding support was provided by the U.S. National Cancer Institute, a member of the National Institutes of Health. The corresponding grant numbers are NCI R01-CA160771 and UL1 RR-025005.
The study lead investigators were Romaric Loffroy, M.D., a radiology fellow at Johns Hopkins, and MingDe Lin, Ph.D., a Philips biomedical engineer based at Johns Hopkins who has been collaborating with Geschwind for the past five years to perfect the DPCBCT technique.
In addition to Geschwind, Loffroy and Lin, other Johns Hopkins researchers involved in this research were Gayane Yenokyan, Ph.D., at the university's Bloomberg School of Public Health; and Pramod Rao, M.D.; Nikhil Bhagat, M.D.; and Eleni Liapi, M.D., all at the School of Medicine. Philips investigators involved were Niels Noordhoek, Ph.D.; Alessandro Radaelli, Ph.D.; and Jarl Blijd, M.Sc.
The chemoembolization research study was funded by Bayer HealthCare and Onyx Pharmaceuticals, manufacturer of sorafenib, and Biocompatibles, makers of the microbeads. Geschwind is a consultant to Bayer HealthCare Pharmaceuticals, and to Biocompatibles. The terms of these arrangements are being managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.
Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

Story Source:

The above story is reprinted from materials provided by Johns Hopkins Medicine, via Newswise.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:
R. Loffroy, M. Lin, G. Yenokyan, P. P. Rao, N. Bhagat, N. Noordhoek, A. Radaelli, J. Blijd, E. Liapi, J.-F. Geschwind. Intraprocedural C-Arm Dual-Phase Cone-Beam CT: Can It Be Used to Predict Short-term Response to TACE with Drug-eluting Beads in Patients with Hepatocellular Carcinoma? Radiology, 2012; DOI: 10.1148/radiol.12112316



Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers. Five Filters recommends: Gaza Blitz - Turmoil And Tragicomedy At The BBC.



You are receiving this email because you subscribed to this feed at http://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
http://blogtrottr.com/unsubscribe/cz0/tSbHWJ

博客归档