Solidot: 肥胖使人变傻，可通过锻炼恢复

Solidot

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肥胖使人变傻，可通过锻炼恢复
http://solidot.org.feedsportal.com/c/33236/f/556826/s/3983b5b7/sc/17/l/0L0Ssolidot0Borg0Cstory0Dsid0F3920A3/story01.htm
Apr 18th 2014, 15:38



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肥胖使人变傻，可通过锻炼恢复



wmr 写道 "在超重的老鼠中，脂肪组织释放的炎性细胞因子会令海马体引发神经炎症，致使学习和记忆能力降低。超重会削弱血脑屏障，其通常会组织炎性细胞因子进入大脑。肥胖人类的脂肪组织亦会产生促炎性因子。Erion et al.发现，跑步训练可以恢复认知缺陷和海马体突触功能。直接切除脂肪也可以产生相同的效果。如果向正常动物注入过多脂肪，也产生了和超重老鼠相似的反应。炎症是脂肪细胞引起的过量Interleukin 1产生的，如果注入抗该蛋白的物质IL1ra，那些影响就会消失。 "






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