Latest Science News -- ScienceDaily: How do polar bears stay warm? Research finds an answer in their genes

Latest Science News -- ScienceDaily

Breaking science news and articles on global warming, extrasolar planets, stem cells, bird flu, autism, nanotechnology, dinosaurs, evolution -- the latest discoveries in astronomy, anthropology, biology, chemistry, climate and environment, computers, engineering, health and medicine, math, physics, psychology, technology, and more -- from the world's leading universities and research organizations.

How do polar bears stay warm? Research finds an answer in their genes
http://feeds.sciencedaily.com/~r/sciencedaily/~3/FTZHOao8ezM/140210135826.htm
Feb 10th 2014, 18:58

In the winter, brown and black bears go into hibernation to conserve energy and keep warm. But things are different for their Arctic relative, the polar bear. Within this high-latitude species, only pregnant females den up for the colder months. So how do the rest survive the extreme Arctic winters?
New research points to one potential answer: genetic adaptations related to the production of nitric oxide, a compound that cells use to help convert nutrients from food into energy or heat.
In a new study, a team led by the University at Buffalo reports that genes controlling nitric oxide production in the polar bear genome contain genetic differences from comparable genes in brown and black bears.
"With all the changes in the global climate, it becomes more relevant to look into what sorts of adaptations exist in organisms that live in these high-latitude environments," said lead researcher Charlotte Lindqvist, PhD, UB assistant professor of biological sciences.
"This study provides one little window into some of these adaptations," she said. "Gene functions that had to do with nitric oxide production seemed to be more enriched in the polar bear than in the brown bears and black bears. There were more unique variants in polar bear genes than in those of the other species."
The paper, titled "Polar Bears Exhibit Genome-Wide Signatures of Bioenergetic Adaptation to Life in the Arctic Environment," appeared Feb. 6 in the journal Genome Biology and Evolution. Co-authors include scientists from UB, Penn State University, the U.S.G.S. Alaska Science Center, Durham University and the University of California, Santa Cruz.
The genetic adaptations the research team saw are important because of the crucial role that nitric oxide plays in energy metabolism.
Typically, cells transform nutrients into energy. However, there is a phenomenon called adaptive or non-shivering thermogenesis, where the cells will produce heat instead of energy in response to a particular diet or environmental conditions.
Levels of nitric oxide production may be a key switch triggering how much heat or energy is produced as cells metabolize nutrients, or how much of the nutrients is stored as fat, Lindqvist said.
"At high levels, nitric oxide may inhibit energy production," said Durham University's Andreanna Welch, PhD, first author and a former postdoctoral researcher at UB with Lindqvist. "At more moderate levels, however, it may be more of a tinkering, where nitric oxide is involved in determining whether -- and when -- energy or heat is produced."
The research is part of a larger research program devoted to understanding how the polar bear has adapted to the harsh Arctic environment, Lindqvist said.
In 2012, she and colleagues reported sequencing the genomes of multiple brown bears, black bears and polar bears.
In a paper in the Proceedings of the National Academy of Sciences, the team said comparative studies between the DNA of the three species uncovered some distinctive polar bear traits, such as genetic differences that may affect the function of proteins involved in the metabolism of fat -- a process that's very important for insulation.
In the new study, the scientists looked at the mitochondrial and nuclear genomes of 23 polar bears, three brown bears and a black bear.

Story Source:
The above story is based on materials provided by University at Buffalo. The original article was written by Charlotte Hsu. Note: Materials may be edited for content and length.
This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers.



You are receiving this email because you subscribed to this feed at https://blogtrottr.com

If you no longer wish to receive these emails, you can unsubscribe here:
https://blogtrottr.com/unsubscribe/cz0/tSbHWJ