2014年5月8日星期四

Solidot: 科学家创造出合成碱基对

Solidot

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科学家创造出合成碱基对
http://solidot.org.feedsportal.com/c/33236/f/556826/s/3a3023eb/sc/17/l/0L0Ssolidot0Borg0Cstory0Dsid0F39452/story01.htm
May 8th 2014, 08:12


DNA遗传编码是由两种天然碱基对(A和T,C和G)构成。现在,科学家在《自然》上发表论文,报告他们创造了非天然碱基对,用非天然碱基对构成的DNA成功的融合在大肠杆菌细胞中。在DNA双链之间,四种天然碱基相互配对,形成了DNA的双螺旋结构。加州Scripps研究院的研究人员开发出一对非天然碱基对(d5SICSTP和dNaMT),他们让这两种分子合成在细菌质体DNA中,再将质体植入大肠杆菌。这段带有新字母的DNA成功在细菌中复制还有转录,而且当细菌分裂时,还会带着这段独特的质体一起分裂。This entry passed through the Full-Text RSS service — if this is your content and you're reading it on someone else's site, please read the FAQ at fivefilters.org/content-only/faq.php#publishers.



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